ArticleMammalian genome : official journal of the International Mammalian Genome Society1993
Partial inversion of gene order within a homologous segment on the X chromosome.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Comparative mapping of X chromosomes in vole species of the genus Microtus.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 1998Article
- Characterization and mapping of the mouse NDP (Norrie disease) locus (Ndp).Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
- A putative human equivalent of the murine Xlr (X-linked, lymphocyte-regulated) protein.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Genetic analyses of tattered, an X-linked dominant, developmental mouse mutation.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- The mouse scurfy (sf) mutation is tightly linked to Gata1 and Tfe3 on the proximal X chromosome.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Mouse homologues of human hereditary disease.Journal of medical genetics · 1994Review
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2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The locus for the erthyroid transcription factor, GATA1, has been positioned in the small interval between DXS255 and TIMP on the proximal short arm of the human X Chromosome (Chr) by use of a partial human cDNA clone and a well-characterized somatic cell hybrid panel. Analysis of selected recombinants from 108 Mus musculus x Mus spretus backcross progeny with the same clone confirmed that the homologous murine locus (Gf-1) lies between Otc and the centromere of the mouse X Chr. These data imply that a partial inversion of gene order has occurred within the conserved segment that represents Xp21.1-Xp11.23 in human (CYBB-GATA1) and the proximal 6 cM of the mouse X Chr (Gf-1-Timp). Furthermore, they indicate that the mouse mutant scurfy and the human genetic disorder Wiskott-Aldrich syndrome, which have been mapped to the same regions as GATA1/Gf-1 in both species, may indeed be homologous disorders.
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