ArticleMammalian genome : official journal of the International Mammalian Genome Society1993
The identification of Y chromosome-linked markers with random sequence oligonucleotide primers.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Cutting edge: the Y chromosome controls the age-dependent experimental allergic encephalomyelitis sexual dimorphism in SJL/J mice.Journal of immunology (Baltimore, Md. : 1950) · 2009Article
- Evidence that the Y chromosome influences autoimmune disease in male and female mice.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Identification and genetic mapping of random amplified polymorphic DNA (RAPD) markers to the sheep genome.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
- Fine genetic mapping of the region surrounding the high growth (hg) locus in mouse chromosome 10: targeting random amplified polymorphic DNA (RAPD) markers.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
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Authors and funding
6 authors.
Funding
Abstract
The polymerase chain reaction (PCR)-based technique of random amplification of polymorphic DNA (RAPD) is extremely useful for developing DNA-based markers. We previously identified a linkage group of eight unmapped RAPD markers that distinguish C57BL/6J and DBA/2J mice (Mammalian Genome 3: Woodward et al., 73-78, 1992). In this study, we report that all eight markers are Y Chromosome (Chr)-linked. One additional Y-linked RAPD was discovered serendipitously during the screening of a C3H/HeJ x (C3H/HeJ x SJL/J)F1 BC1 population. The segregation of all nine markers was analyzed with a panel of 14 independent inbred strains of male mice. The nine markers could be divided into three distinct groups: (1) DYByu2, DYByu5, DYByu6, and DYByu8 identify both the M.m. musculus and M.m. domesticus type Y Chr; (2) DYByu1, DYByu3, DYByu4, and DYByu7 are specific for the M.m. musculus type; and (3) DYByu9 is specific for the M.m. domesticus type. The results clearly indicate that the RAPD technique can be used to identify Y Chr-linked, DNA-based markers in mammalian species.
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