Evidence map›Paper›PMID 8422501›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society1993

Chromosomal assignment of the recoverin gene and cancer-associated retinopathy.

J F McGinnis, V Lerious, J Pazik, R W Elliott

Abstract read
PubMed Publisher
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Retinopathies associated with antiretinal antibodies.Clinical and diagnostic laboratory immunology · 2001
    Review
  3. Localization of three genes expressed in retina on mouse chromosome 11.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

J F McGinnisDepartment of Anatomy and Cell Biology, University of California Los Angeles 90024.
V Lerious
J Pazik
R W Elliott
New York State Department of Health · USUniversity of California, Los Angeles · US

Funding

MOLECULAR CHARACTERIZATION OF THE RHODOPSIN GENER01EY006639 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCGINNIS, JAMES FRANCIS · 1986 to 1994
–
DETECTING AND MAPPING SEQUENCE CHANGES IN MOUSE DNAR01GM028464 · NIGMS · ROSWELL PARK CANCER INSTITUTE · PI ELLIOTT, ROSEMARY W · 1985 to 1989
–
NEI NIH HHS EY06085NEI NIH HHS EY06639NIGMS NIH HHS GM28464
6 · The paper itself

Abstract

The deduced amino acid sequence of the recently cloned mouse 23kD photoreceptor cell-specific protein showed it to be identical to the recoverin protein and the CAR (cancer-associated retinopathy) protein. DNA sequence variants were found in the mouse recoverin gene (Rcvrn), and segregation analysis of restriction fragment length variants in recombinant inbred strains of mice assigned Rcvrn to mouse Chromosome (Chr) 11, between Sparc (3.7 map units) and Zfp-3 (2.3 map units). These results demonstrate a close linkage of recoverin to the tumor suppressor gene, Trp53. On the basis of these data, knowledge of the function of recoverin, and the characteristics of CAR, an experimentally testable model is presented to explain the molecular basis for CAR.

Indexed as

Chromosome MappingEye ProteinsLipoproteinsNerve Tissue ProteinsAnimalsAntigens, NeoplasmBlotting, SouthernCalcium-Binding ProteinsGenes, Tumor SuppressorGenetic LinkageHippocalcinMiceMice, Inbred C57BLMice, Inbred DBARecoverinAntigens, NeoplasmCalcium-Binding ProteinsEye ProteinsHippocalcinLipoproteinsNerve Tissue ProteinsRcvrn protein, mouseRecoverin

Identifiers

PMID8422501
OpenAlexW1968483583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.