ArticleThe Journal of cell biology1993
Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6).
Article in The Journal of cell biology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 116 citations in OpenAlex.
- Article
- Cooperation of TGF-β and FGF signalling pathways in skin development.Cell proliferation · 2023Review
- BMP6 Regulates Corneal Epithelial Cell Stratification by Coordinating Their Proliferation and Differentiation and Is Upregulated in Pterygium.Investigative ophthalmology & visual science · 2020Article
- BMP6-induced modulation of the tumor micro-milieu.Oncogene · 2019Article
- Smad1 and 5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis toward the postnatal state.Stem cells (Dayton, Ohio) · 2014Article
- Bone morphogenetic proteins: periodontal regeneration.North American journal of medical sciences · 2013Article
- BMP7 gene transfer via gold nanoparticles into stroma inhibits corneal fibrosis in vivo.PloS one · 2013Article
- Overexpression of constitutively active BMP-receptor-IB in mouse skin causes an ichthyosis-vulgaris-like disease.Cell and tissue research · 2010Article
- Clustering by neurocognition for fine mapping of the schizophrenia susceptibility loci on chromosome 6p.Genes, brain, and behavior · 2009Article
- p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.The Journal of biological chemistry · 2009Article
- Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue.Development (Cambridge, England) · 2009Article
- Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway.The American journal of pathology · 2004Article
- Glia induce dendritic growth in cultured sympathetic neurons by modulating the balance between bone morphogenetic proteins (BMPs) and BMP antagonists.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Article
- Bone morphogenetic protein-6 production in human osteoblastic cell lines. Selective regulation by estrogen.The Journal of clinical investigation · 1998Article
- Structure and sequence of the mouse Bmp6 gene.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions.The Journal of cell biology · 1996Article
- Insulin-like growth factor-I (IGF-I) colocalizes with IGF-binding proteins (IGFBPs) in mouse and rat ovary.Endocrine · 1996Article
- Bone morphogenetic protein-6 expression in normal and malignant prostate.World journal of urology · 1995Article
- Recombinant Vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo.The Journal of cell biology · 1994Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
DVR-6 (BMP-6 or Vgr-1) is a member of the TGF-beta superfamily of polypeptide signaling molecules. In situ hybridization studies have previously shown that DVR-6 RNA is expressed in a variety of cell types in the mouse embryo, but no information has been available on protein localization and biosynthesis. We have produced a polyclonal antibody to the proregion of DVR-6 and used it to localize the protein in whole mount and sectioned embryonic, newborn, and adult mouse tissues. DVR-6 protein is expressed in the mouse nervous system beginning at 9.5 days postcoitum (d.p.c.) and continues through adulthood. A variety of epithelial tissues also produce DVR-6 protein, including the suprabasal layer of the skin, bronchiolar epithelium, and the cornea. Additionally, a stably transfected cell line, BMGE+H/D6c4, is used to study the biosynthesis of DVR-6 protein and evidence is presented for translational regulation of DVR-6 expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.