Evidence map›Paper›PMID 8419069›Full record

ReviewClinical and experimental immunology1993

ANCA and associated diseases: immunodiagnostic and pathogenetic aspects.

W L Gross, W H Schmitt, E Csernok

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
32.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 303 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Limited Granulomatosis With Polyangiitis of Nose and Paranasal Sinuses - a Case Report.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Clinical features and prognostic factors of Churg-Strauss syndrome.The Korean journal of internal medicine · 2014
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Small-vessel vasculitis.Current rheumatology reports · 2007
    Review
  18. Article
  19. Article
  20. [Pulmonary-renal syndrome].Der Internist · 2005
    Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

W L GrossDepartment of Clinical Rheumatology, Medical University of Lübeck, Bad Bramstedt, Germany.
W H Schmitt
E Csernok
HNO Bad Bramstedt · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past decade has seen an explosion of data on the new group of autoantibodies known collectively as ANCA (anti-neutrophil cytoplasmic antibodies). ANCA are specific for granule proteins of granulocytes and monocytes and induce distinct fluorescence patterns, e.g. the cytoplasmic (classic) cANCA and the perinuclear pANCA. cANCA is induced by antibodies directed against Proteinase 3 (PR3; PR3-ANCA) in about 90% of all ANCA-positive sera, and pANCA is induced by antibodies against myeloperoxidase (MPO; MPO-ANCA) in about 40%. A further staining pattern, which does not have a clear cut association with a distinct granule protein, is sometimes seen in chronic inflammatory bowel diseases. PR3-ANCA are serological markers for Wegener's granulomatosis (WG) and MPO-ANCA are associated with certain subtypes of primary vasculitides. Evidence exists that both the autoantigen and ANCA participate in the pathogenesis of at least the group of 'ANCA-associated vasculitides'.

Indexed as

AnimalsAntibodies, Antineutrophil CytoplasmicAutoantibodiesAutoantigensChronic DiseaseEndotheliumGranulomatosis with PolyangiitisHumansInflammatory Bowel DiseasesKidney DiseasesVasculitisAntibodies, Antineutrophil CytoplasmicAutoantibodiesAutoantigens

Identifiers

PMID8419069
PMCPMC1554662
OpenAlexW2037892270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.