Evidence map›Paper›PMID 8415722›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1993

The yeast Candida albicans has a clonal mode of reproduction in a population of infected human immunodeficiency virus-positive patients.

C Pujol, J Reynes, F Renaud, M Raymond, M Tibayrenc, F J Ayala, F Janbon, M Mallié, J M Bastide

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 176 citations in OpenAlex.

  1. White-opaque switching inMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  2. Article
  3. Review
  4. Article
  5. Parasexuality ofFrontiers in cellular and infection microbiology · 2021
    Review
  6. Identification of Key Candidate Genes and Pathways ofIndian journal of microbiology · 2020
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. The frequency of sex in fungi.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C PujolLaboratoire d'Immunologie et Parasitologie, Faculté de Pharmacie, Montpellier, France.
J Reynes
F Renaud
M Raymond
M Tibayrenc
F J Ayala
F Janbon
M Mallié
J M Bastide

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To ascertain the population structure of Candida albicans, we have carried out a multilocus enzyme electrophoresis study based on the analysis of 21 gene loci. We have thus characterized 55 strains isolated one each from 55 human immunodeficiency virus-positive patients. There is considerable polymorphism among the strains. A population-genetic analysis indicates that the two fundamental consequences of sexual reproduction (i.e., segregation and recombination) are apparently absent in this population of C. albicans. The population structure of C. albicans appears to be clonal, a state of affairs that has important medical and biological consequences.

Indexed as

Candida albicansCandidiasisClone CellsGenetic LinkageGenetics, PopulationHeterozygoteHIV SeropositivityHumansIsoenzymesPolymorphism, GeneticIsoenzymes

Identifiers

PMID8415722
PMCPMC47587
OpenAlexW2141048809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.