ArticleProceedings of the National Academy of Sciences of the United States of America1993
Regional expression and chromosomal localization of the delta opiate receptor gene.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- Enkephalins and Pain Modulation: Mechanisms of Action and Therapeutic Perspectives.Biomolecules · 2024Review
- microRNA-874 suppresses tumor proliferation and metastasis in hepatocellular carcinoma by targeting the DOR/EGFR/ERK pathway.Cell death & disease · 2018Article
- Molecular Pharmacology of δ-Opioid Receptors.Pharmacological reviews · 2016Review
- IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes.The Journal of cell biology · 2015Article
- A new splice of life for the μ-opioid receptor.The Journal of clinical investigation · 2015Article
- Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives.Clinical pharmacokinetics · 2004Review
- Candidate genes for anorexia nervosa in the 1p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa.Molecular psychiatry · 2003Article
- Estrogen stimulates postsynaptic density-95 rapid protein synthesis via the Akt/protein kinase B pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Developmental expression of the mu, kappa, and delta opioid receptor mRNAs in mouse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The delta opiate receptor gene has been cloned from the mouse neuroblastoma-rat glioma hybrid cell NG108-15. The clone that we isolated is apparently identical to that reported by Evans et al. [Evans, C. J., Keith, D. E., Jr., Morrison, H., Magendzo, K. & Edwards, R. H. (1992) Science 258, 1952-1955] and essentially identical with that of Kieffer et al. [Kieffer, B. L., Befort, K., Gaveriaux-Ruff, C. & Hirth, C. G. (1992) Proc. Natl. Acad. Sci. USA 89, 12048-12052]. We have found full-length transcripts of the gene in mouse brain but in no other tissues examined. Within the brain the gene is expressed at low levels in many regions but transcripts are found in particularly large amounts in the anterior pituitary and pineal glands. Since these tissues are located outside the blood-brain barrier, opioid peptides easily can reach receptors in these areas from the blood. The gene, which is present as a single copy, has been mapped to the distal region of mouse Chromosome 4.
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Registered trials
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