ArticleJournal of comparative pathology1993
Relationship between onset of puberty and establishment of persistent infection with equine arteritis virus in the experimentally infected colt.
Article in Journal of comparative pathology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Identification of Equine Arteritis Virus Immunodominant Epitopes Using a Peptide Microarray.Viruses · 2022Article
- Article
- Intrahost Selection Pressure Drives Equine Arteritis Virus Evolution during Persistent Infection in the Stallion Reproductive Tract.Journal of virology · 2019Article
- Equine Arteritis Virus Elicits a Mucosal Antibody Response in the Reproductive Tract of Persistently Infected Stallions.Clinical and vaccine immunology : CVI · 2017Article
- Equine Arteritis Virus Has Specific Tropism for Stromal Cells and CD8Journal of virology · 2017Article
- Curing of HeLa cells persistently infected with equine arteritis virus by a peptide-conjugated morpholino oligomer.Virus research · 2010Article
- Persistent equine arteritis virus infection in HeLa cells.Journal of virology · 2008Article
- Lymphoid tissue tropism of porcine reproductive and respiratory syndrome virus replication during persistent infection of pigs originally exposed to virus in utero.Veterinary microbiology · 2003Article
- Monoclonal antibodies directed against conserved epitopes on the nucleocapsid protein and the major envelope glycoprotein of equine arteritis virus.Journal of clinical microbiology · 2000Article
- Porcine reproductive and respiratory syndrome virus replicates in testicular germ cells, alters spermatogenesis, and induces germ cell death by apoptosis.Journal of virology · 1997Article
- Equine arteritis virus.Theriogenology · 1997Article
- Pseudocyst of the testis of a prepubertal horse.The Canadian veterinary journal = La revue veterinaire canadienne · 1995Article
- Equine viral arteritis.The Veterinary clinics of North America. Equine practice · 1993Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between stage of reproductive tract maturity and susceptibility to the experimental establishment of persistent infection with equine arteritis virus (EAV) was investigated in 21 prepubertal and 15 peripubertal colts. Five of six prepubertal colts inoculated intranasally remained infected in the reproductive tract from post-challenge day 28 to 93 and two of six from post-challenge day 120 to 180. No virus was detected in five of these animals killed on post-challenge day 210. Each of two peripubertal colts remained infected in the reproductive tract at post-challenge day 60 and one of nine was found to be persistently infected with EAV 15 months after challenge. These findings confirm that the virus can replicate in the reproductive tract of a significant proportion of colts for a variable period of time after clinical recovery in the absence of circulating concentrations of testosterone equivalent to those found in sexually mature stallions. Long-term persistent infection with EAV does not appear to occur in colts exposed to the virus before the onset of peripubertal development. We suggest that colts should be vaccinated at approximately 6 months of age, before peripubertal development but after the disappearance of maternally acquired antibodies.
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