ArticleInfection and immunity1993
Effect of type III group B streptococcal capsular polysaccharide on invasion of respiratory epithelial cells.
Article in Infection and immunity, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 71 citations in OpenAlex.
- Gamma-Irradiated Non-Capsule Group B Streptococcus Promotes T-Cell Dependent Immunity and Provides a Cross-Protective Reaction.Pharmaceuticals (Basel, Switzerland) · 2023Article
- The Double Life of Group B Streptococcus: Asymptomatic Colonizer and Potent Pathogen.Journal of molecular biology · 2019Review
- Bacteriophage Resistance Alters Antibiotic-Mediated Intestinal Expansion of Enterococci.Infection and immunity · 2019Article
- Exopolysaccharide-mediated surface penetration as new virulence trait inCommunicative & integrative biology · 2019Article
- Diminished Capsule Exacerbates Virulence, Blood-Brain Barrier Penetration, Intracellular Persistence, and Antibiotic Evasion of Hyperhemolytic Group B Streptococci.The Journal of infectious diseases · 2018Article
- A cytosol derived factor of Group B streptococcus prevent its invasion into human epithelial cells.World journal of microbiology & biotechnology · 2018Article
- Group B Streptococcus interactions with human meningeal cells and astrocytes in vitro.PloS one · 2012Article
- Further characterization of the epa gene cluster and Epa polysaccharides of Enterococcus faecalis.Infection and immunity · 2009Article
- Understanding the regulation of Group B Streptococcal virulence factors.Future microbiology · 2009Review
- Bacterial phenotype variants in group B streptococcal toxic shock syndrome.Emerging infectious diseases · 2009Article
- Identification of genes associated with the long-gut-persistence phenotype of the probiotic Lactobacillus johnsonii strain NCC533 using a combination of genomics and transcriptome analysis.Journal of bacteriology · 2008Article
- Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish.Journal of bacteriology · 2007Article
- The streptococcal Blr and Slr proteins define a family of surface proteins with leucine-rich repeats: camouflaging by other surface structures.Journal of bacteriology · 2006Article
- The novel fibrinogen-binding protein FbsB promotes Streptococcus agalactiae invasion into epithelial cells.Infection and immunity · 2004Article
- C3 promotes clearance of Klebsiella pneumoniae by A549 epithelial cells.Infection and immunity · 2004Article
- Oxygen regulates invasiveness and virulence of group B streptococcus.Infection and immunity · 2003Article
- Role of lung epithelial cells in defense against Klebsiella pneumoniae pneumonia.Infection and immunity · 2002Article
- Use of a dynamic in vitro attachment and invasion system (DIVAS) to determine influence of growth rate on invasion of respiratory epithelial cells by group B Streptococcus.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Changes in availability of oxygen accentuate differences in capsular polysaccharide expression by phenotypic variants and clinical isolates of Streptococcus pneumoniae.Infection and immunity · 2001Article
- Nonopsonic binding of type III Group B Streptococci to human neutrophils induces interleukin-8 release mediated by the p38 mitogen-activated protein kinase pathway.Infection and immunity · 2000Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Group B streptococcal (GBS) capsular polysaccharide is an important virulence factor, and its role in invasion of cultured respiratory epithelial cells was investigated. A type III GBS clinical isolate, COH1, and asialo and unencapsulated isogenic transposon capsule mutants of it were compared in an in vitro invasion assay. The results demonstrated that capsule attenuated the invasion process. Invasion was not affected when the A549 epithelial cells were preincubated with purified type III GBS capsular polysaccharide. Polyclonal type III GBS capsule antibody inhibited invasion by COH1 but did not affect invasion by the capsule mutants. Serotypes Ia, Ib, Ia/c, II, and III all invaded respiratory epithelial cells but demonstrated some strain variation in magnitude of invasion. These observations led us to conclude that type III capsular polysaccharide was not essential for invasion of respiratory epithelial cells by GBS and that bacterial factors other than capsule were responsible for respiratory epithelial cell invasion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.