Trial reportEuropean journal of clinical pharmacology1993
The analgesic efficacy of diclofenac dispersible and ibuprofen in postoperative pain after dental extraction.
Trial report in European journal of clinical pharmacology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Single dose oral diclofenac for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2015Pooled it
- Single dose oral ibuprofen for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2009Pooled it
- Single dose oral diclofenac for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2009Pooled it
- A Meta-Analysis of the Analgesic Efficacy of Single-Doses of Ibuprofen Compared to Traditional Non-Opioid Analgesics Following Third Molar Surgery.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Pain management for dentists: the role of ibuprofen.Annali di stomatologia · 2011Article
- Maximizing the safety of nonsteroidal anti-inflammatory drug use for postoperative dental pain: an evidence-based approach.Anesthesia progress · 2003Review
- Summary of the scientific literature for pain and anxiety control in dentistry.Anesthesia progress · 1994Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have compared single oral doses of drinkable diclofenac dispersible (50 mg) with ibuprofen (400 mg) and placebo in a randomized, double-blind, parallel-group trial in 127 adults complaining of at least moderately severe pain after removal of an impacted third molar. Within 40 min both diclofenac and ibuprofen produced significant pain relief that persisted for 6 h. There were no differences between diclofenac and ibuprofen in analgesic efficacy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.