ArticleBMJ (Clinical research ed.)1993
Screening for carriers of cystic fibrosis--a general practitioner's perspective.
Article in BMJ (Clinical research ed.), 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Cystic fibrosis carrier population screening in the primary care setting.American journal of human genetics · 1996Trial
- Carrier screening in preconception consultation in primary care.Journal of community genetics · 2012Article
- Attitudes toward cystic fibrosis carrier and prenatal testing and utilization of carrier testing among relatives of individuals with cystic fibrosis.Journal of genetic counseling · 1999Article
- Costs, effects, and savings of screening for cystic fibrosis gene carriers.Journal of epidemiology and community health · 1998Article
- The views of general practitioners on community carrier screening for cystic fibrosis.The British journal of general practice : the journal of the Royal College of General Practitioners · 1996Article
- Screening for carriers of cystic fibrosis. Screening before pregnancy is needed.BMJ (Clinical research ed.) · 1994Article
- Active cascade testing for carriers of cystic fibrosis gene.BMJ (Clinical research ed.) · 1994Article
- Clinical genetics meets primary care.BMJ (Clinical research ed.) · 1993Article
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1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The identification of the gene for cystic fibrosis has led to the possibility of population based screening for carriers of cystic fibrosis to identify couples at risk of having an affected child. Pilot studies have shown that screening is feasible and does not cause untoward anxiety, though the uptake of testing varies considerably with the setting and method of invitation. Screening offered at times when individuals (and health professionals) perceive it as directly relevant will probably gradually become established in the United Kingdom. This review examines the role of general practice in genetic carrier screening as exemplified by cystic fibrosis. General practice has a pivotal role from the beginning in providing individuals and couples with information, facilitating testing of patients' relatives and of carriers identified by screening elsewhere (such as antenatal clinics), and offering testing in the context of reproduction. Screening for the cystic fibrosis gene will probably be followed by other genetic screening programmes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.