ArticleInternational journal of experimental pathology1993
Stimulation of neutrophil respiratory burst and degranulation by Japanese encephalitis virus-induced macrophage derived factor.
Article in International journal of experimental pathology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Integrating host transcriptomic signatures for distinguishing autoimmune encephalitis in cerebrospinal fluid by metagenomic sequencing.Cell & bioscience · 2023Article
- An enzyme immunoassay for detection of Japanese encephalitis virus-induced chemotactic cytokine.Journal of biosciences · 2000Article
- Degradation of Japanese encephalitis virus by neutrophils.International journal of experimental pathology · 1999Article
- Viruria during acute Japanese encephalitis virus infection.International journal of experimental pathology · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of Japanese encephalitis virus (JEV) and JEV-induced macrophage derived neutrophil chemotactic factor (MDF) on respiratory burst and granule exocytosis in neutrophils were studied and were compared with N-formyl-methionyl-leucyl-phenylalanine (FMLP). JEV-stimulated neutrophils released reactive oxygen metabolites with maximum activity between days 7 and 9. The response in mice was sensitive to anti-JEV-antisera treatment. Stimulation by MDF resulted in quick release of superoxide and granule enzymes from neutrophils upon both in-vivo and in-vitro stimulation in a dose dependent manner. The effect was abrogated by the MDF-specific antisera treatment. These responses were similar in kinetics and magnitude to those produced in response to FMLP. The respiratory burst elicited by MDF was abrogated by staurosporine, indicating that neutrophil activation and signal transduction by MDF and FMLP are dependent on protein kinase C.
Indexed as
Identifiers
8398806PMC2001854W1012203882What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.