ArticleJournal of clinical microbiology1993
Comparison of restriction enzyme analysis versus pulsed-field gradient gel electrophoresis as a typing system for Torulopsis glabrata and Candida species other than C. albicans.
Article in Journal of clinical microbiology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 75 citations in OpenAlex.
- Multiechinocandin- and multiazole-resistant Candida parapsilosis isolates serially obtained during therapy for prosthetic valve endocarditis.Antimicrobial agents and chemotherapy · 2005Article
- Multilocus sequence typing of Candida glabrata reveals geographically enriched clades.Journal of clinical microbiology · 2003Article
- Genetic diversity among clinical isolates of Candida glabrata analyzed by randomly amplified polymorphic DNA and multilocus enzyme electrophoresis analyses.Journal of clinical microbiology · 2003Article
- Molecular mechanisms of itraconazole resistance in Candida dubliniensis.Antimicrobial agents and chemotherapy · 2003Article
- Primers ITS1, ITS2 and ITS4 detect the intraspecies variability in the internal transcribed spacers and 5.8S rRNA gene region in clinical isolates of fungi.Folia microbiologica · 2003Article
- Mitochondrial telomeres as molecular markers for identification of the opportunistic yeast pathogen Candida parapsilosis.Journal of clinical microbiology · 2002Article
- Alternative identification test relying upon sexual reproductive abilities of Candida lusitaniae strains isolated from hospitalized patients.Journal of clinical microbiology · 2001Article
- The ins and outs of DNA fingerprinting the infectious fungi.Clinical microbiology reviews · 2000Review
- Biotyping and virulence properties of skin isolates of Candida parapsilosis.Journal of clinical microbiology · 1999Article
- High-frequency, in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericin B susceptibility to resistance.Antimicrobial agents and chemotherapy · 1999Article
- Nosocomial Candida glabrata colonization: an epidemiologic study.Journal of clinical microbiology · 1998Article
- Confirmation of the distinct genotype groups within the form species Candida parapsilosis.Journal of clinical microbiology · 1998Article
- Identification of Candida species by randomly amplified polymorphic DNA fingerprinting of colony lysates.Journal of clinical microbiology · 1997Article
- Development of two species-specific fingerprinting probes for broad computer-assisted epidemiological studies of Candida tropicalis.Journal of clinical microbiology · 1996Article
- Techniques for investigation of an apparent outbreak of infections with Candida glabrata.Journal of clinical microbiology · 1996Article
- Evaluation of pulsed-field gel electrophoresis as a typing system for Candida rugosa: comparison of karyotype and restriction fragment length polymorphisms.Journal of clinical microbiology · 1996Article
- History of medical mycology in the united states.Clinical microbiology reviews · 1996Article
- Rapid identification of Candida species by DNA fingerprinting with PCR.Journal of clinical microbiology · 1996Article
- Contribution of molecular typing methods and antifungal susceptibility testing to the study of a candidemia cluster in a burn care unit.Journal of clinical microbiology · 1995Article
- Comparison of four DNA-based methods for strain delineation of Candida lusitaniae.Journal of clinical microbiology · 1995Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candida species have recently emerged as important nosocomial pathogens. Because of the lack of a reliable system for detecting differences within the same species, little is known about the epidemiology of infection with Candida species. We describe a typing system for Torulopsis glabrata and the non-C. albicans Candida species that uses contour-clamped homogeneous electric field electrophoresis (CHEF), a version of pulsed-field gradient gel electrophoresis, and compared it with restriction enzyme analysis (REA) of genomic DNA. One hundred seventeen clinical isolates from 40 patients were evaluated. CHEF and REA were performed on each of the isolates, and the results of the two procedures were compared. The REA procedure revealed 8 different types of Candida lusitaniae, 20 of Torulopsis glabrata, 5 of Candida tropicalis, 3 of Candida parapsilosis, and 7 of Candida kefyr, whereas the CHEF method revealed 14 different types of C. lusitaniae, 16 of T. glabrata, 10 of C. tropicalis, 10 of C. parapsilosis, and 7 of C. kefyr. The CHEF technique yielded unique patterns of electrophoretic karyotypes that could be used to distinguish intraspecies variations. When compared with REA, CHEF demonstrated greater sensitivity in recognizing subtle strain-to-strain variations in most isolates and will be a useful epidemiologic tool for studying non-C. albicans Candida species and T. glabrata.
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