ArticleThe Journal of experimental medicine1993
Peripheral selection of V delta 1+ cells with restricted T cell receptor delta gene junctional repertoire in the peripheral blood of healthy donors.
Article in The Journal of experimental medicine, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
- Human Vδ1Frontiers in immunology · 2019Review
- Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection.Nature immunology · 2017Article
- Cytotoxic and regulatory properties of circulating Vδ1+ γδ T cells: a new player on the cell therapy field?Molecular therapy : the journal of the American Society of Gene Therapy · 2014Review
- The evolution of clonality testing in the diagnosis and monitoring of hematological malignancies.Therapeutic advances in hematology · 2014Review
- EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations.Leukemia · 2012Review
- Human cytomegalovirus elicits fetal gammadelta T cell responses in utero.The Journal of experimental medicine · 2010Article
- Article
- Aortic aneurysms: an immune disease with a strong genetic component.Circulation · 2008Review
- Skewed T cell receptor repertoire of Vdelta1(+) gammadelta T lymphocytes after human allogeneic haematopoietic stem cell transplantation and the potential role for Epstein-Barr virus-infected B cells in clonal restriction.Clinical and experimental immunology · 2007Article
- Review
- Implication of gammadelta T cells in the human immune response to cytomegalovirus.The Journal of clinical investigation · 1999Article
- Article
- The delta T cell receptor repertoire in human colon and peripheral blood is oligoclonal irrespective of V region usage.The Journal of clinical investigation · 1995Article
- Gamma delta T cell receptor gene expression by muscle-infiltrating lymphocytes in the idiopathic inflammatory myopathies.Clinical and experimental immunology · 1995Article
- The enigmatic specificity of gamma delta T cells.Immunologic research · 1995Review
- Distribution of dominant T cell receptor beta chains in human intestinal mucosa.The Journal of experimental medicine · 1994Article
- The V delta 1 T cell receptor repertoire in human small intestine and colon.The Journal of experimental medicine · 1994Article
- Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".The Journal of experimental medicine · 1994Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To characterize the T cell receptor (TCR) repertoire expressed by the V delta 1+ gamma/delta T cell population, we have studied the V delta 1-J delta 1 junctional sequences from peripheral blood samples of healthy donors. We show that, surprisingly, this repertoire is restricted in most healthy adults, with a donor-specific and relatively stable pattern, whereas this repertoire remains unrestricted in infants, and is similar to that of thymocytes. These data contrast with the general assumption that the junctional repertoire of V delta 1+ gamma/delta T cells is extensive, and strongly suggest that peripheral recruitment of V delta 1+ cells bearing particular TCR occurs in humans during the postnatal stage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.