ArticleAnnals of the rheumatic diseases1993
Occurrence of autoantibodies to human leucocyte elastase in Wegener's granulomatosis and other inflammatory disorders.
Article in Annals of the rheumatic diseases, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 116 citations in OpenAlex.
- Antineutrophil cytoplasmic antibody-negative granulomatosis with polyangiitis localized to the lungs.Respiratory medicine case reports · 2022Article
- A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.Nature communications · 2019Article
- Unraveling the identity of FoxP3+ regulatory T cells in Granulomatosis with Polyangiitis patients.Scientific reports · 2019Article
- CD27Frontiers in immunology · 2019Article
- Optimal management of Cogan's syndrome: a multidisciplinary approach.Journal of multidisciplinary healthcare · 2018Review
- Autoimmune Inner Ear Disease: Immune Biomarkers, Audiovestibular Aspects, and Therapeutic Modalities of Cogan's Syndrome.Journal of immunology research · 2018Review
- Chemokine receptor co-expression reveals aberrantly distributed TArthritis research & therapy · 2017Article
- Prospective monitoring of in vitro produced PR3-ANCA does not improve relapse prediction in granulomatosis with polyangiitis.PloS one · 2017Article
- Cogan's syndrome and other ocular vasculitides.Current rheumatology reports · 2015Review
- New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.The Journal of biological chemistry · 2014Article
- Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis.The Journal of clinical investigation · 2013Article
- Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).Arthritis research & therapy · 2013Article
- Antineutrophil cytoplasmic autoantibodies: how are they detected and what is their use for diagnosis, classification and follow-up?Clinical reviews in allergy & immunology · 2012Review
- Pathogenesis of ANCA-associated vasculitis.Current rheumatology reports · 2012Review
- Increased expression of Toll-like receptors by monocytes and natural killer cells in ANCA-associated vasculitis.PloS one · 2011Article
- Pathogenesis of ANCA-associated vasculitis.Rheumatic diseases clinics of North America · 2010Review
- IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.Journal of the American Society of Nephrology : JASN · 2010Article
- Standardised assessment of membrane proteinase 3 expression. Analysis in ANCA-associated vasculitis and controls.Annals of the rheumatic diseases · 2007Article
- Translational mini-review series on vaccines: Peptide vaccines for myeloid leukaemias.Clinical and experimental immunology · 2007Review
- Plasma levels of soluble interleukin 2 receptor, soluble CD30, interleukin 10 and B cell activator of the tumour necrosis factor family during follow-up in vasculitis associated with proteinase 3-antineutrophil cytoplasmic antibodies: associations with disease activity and relapse.Annals of the rheumatic diseases · 2006Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antineutrophil cytoplasmic antibodies (ANCAs) constitute a new class of autoantibodies that seem to recognise myeloid lysosomal enzymes. The occurrence of ANCAs with specificity for human leucocyte elastase (HLE) was assessed in serum samples that were routinely submitted for ANCA determination. During a study period of more than six years anti-HLE was found in only six out of 1102 serum samples that produced a perinuclear or an atypical cytoplasmic staining pattern on ethanol fixed granulocytes. These six serum samples were from four patients with a clinical diagnosis of Wegener's granulomatosis but without a definite histological diagnosis, one patient with systemic vasculitis, and one patient with Cogan's syndrome. To further evaluate the prevalence of anti-HLE we tested 315 serum samples from patients with different forms of vasculitis and related disorders. Anti-HLE was detected in two patients only. Thus autoantibodies to HLE are rarely found in serum samples from patients with vasculitic or related disorders.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.