Evidence map›Paper›PMID 8383246›Full record

ArticleJournal of virology1993

Passive antibody protection of cats against feline immunodeficiency virus infection.

T Hohdatsu, R Pu, B A Torres, S Trujillo, M B Gardner, J K Yamamoto

Abstract read
In one paragraph

Article in Journal of virology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Advances in FIV vaccine technology.Veterinary immunology and immunopathology · 2008
    Review
  3. Lentivirus-induced immune dysregulation.Veterinary immunology and immunopathology · 2008
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Passive immunotherapy for retroviral disease: influence of major histocompatibility complex type and T-cell responsiveness.Proceedings of the National Academy of Sciences of the United States of America · 1995
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

T HohdatsuDepartment of Medicine, School of Veterinary Medicine, University of California, Davis 95616.
R Pu
B A Torres
S Trujillo
M B Gardner
J K Yamamoto

Funding

VACCINES FOR FELINE IMMUNODEFICIENCY VIRUSR01AI030904 · NIAID · UNIVERSITY OF FLORIDA · PI YAMAMOTO, JANET K. · 1991 to 2012
$4.2M
Protective CMI mechanisms of a dual-subtype FIV vaccineR56AI030904 · NIAID · UNIVERSITY OF FLORIDA · PI YAMAMOTO, JANET K. · 2008 to 2008
$99k
IMMUNODEFICIENCY RETROVIRUSES IN MAN AND ANIMALSP30AI027732 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI CARLSON, JAMES R · 1988 to 1993
–
FUNCTIONAL &PHENOTYPIC ANALYSIS OF T-CELLS IN FIV-FAIDSR01CA039016 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI YAMAMOTO, JANET K. · 1989 to 1991
–
LYMPHOKINES IN FELV IMMUNOSUPPRESSION AND LEUKEMIAR23CA039016 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI YAMAMOTO, JANET K. · 1985 to 1987
–
NCI NIH HHS CA-39016NIAID NIH HHS AI27732NIAID NIH HHS AI30904
6 · The paper itself

Abstract

All six cats passively immunized with sera from either feline immunodeficiency virus (FIV)-vaccinated cats or cats infected with FIV (Petaluma strain) were protected from homologous FIV infection at a challenge dose that infected all six control cats. Passive immunization with sera from cats vaccinated with uninfected allogeneic T cells used to grow the vaccine virus did not protect either of two cats against the same FIV challenge. These results suggest that antiviral humoral immunity, perhaps in synergy with anticellular antibodies, may be responsible for previously reported vaccine protection.

Indexed as

AnimalsAntibodies, ViralCatsFeline Acquired Immunodeficiency SyndromeImmunization, PassiveImmunodeficiency Virus, FelineNeutralization TestsViral VaccinesAntibodies, ViralViral Vaccines

Identifiers

PMID8383246
PMCPMC240393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.