ArticleNucleic acids research1993
cDNA structure, expression and nucleic acid-binding properties of three RNA-binding proteins in tobacco: occurrence of tissue-specific alternative splicing.
Article in Nucleic acids research, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 79 citations in OpenAlex.
- BpGRP1 acts downstream of BpmiR396c/BpGRF3 to confer salt tolerance in Betula platyphylla.Plant biotechnology journal · 2024Article
- Genome-wide identification, phylogenetic analysis, and expression profiling of glycine-rich RNA-binding protein (GRPs) genes in seeded and seedless grapes (Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana.Nucleic acids research · 2010Article
- Reciprocal regulation of glycine-rich RNA-binding proteins via an interlocked feedback loop coupling alternative splicing to nonsense-mediated decay in Arabidopsis.Nucleic acids research · 2008Article
- Identification of cold-shock protein RBM3 as a possible regulator of skeletal muscle size through expression profiling.American journal of physiology. Regulatory, integrative and comparative physiology · 2008Article
- Characterization of wound-responsive RNA-binding proteins and their splice variants in Arabidopsis.Plant molecular biology · 2008Article
- AtGRP2, a cold-induced nucleo-cytoplasmic RNA-binding protein, has a role in flower and seed development.Planta · 2007Article
- Computational prediction and experimental verification of HVA1-like abscisic acid responsive promoters in rice (Oryza sativa).Plant molecular biology · 2006Article
- Gene expression and genetic mapping analyses of a perennial ryegrass glycine-rich RNA-binding protein gene suggest a role in cold adaptation.Molecular genetics and genomics : MGG · 2006Article
- AtGRP7 is involved in the regulation of abscisic acid and stress responses in Arabidopsis.Cellular & molecular biology letters · 2006Article
- Article
- High expression level of a gene coding for a chloroplastic amino acid selective channel protein is correlated to cold acclimation in cereals.Plant molecular biology · 1999Article
- A glycine-rich RNA-binding protein gene is differentially expressed during acute hypersensitive response following Tobacco Mosaic Virus infection in tobacco.Plant molecular biology · 1998Article
- Root-specific expression of a Zea mays gene encoding a novel glycine-rich protein, zmGRP3.Plant molecular biology · 1998Article
- Article
- A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth.The Journal of cell biology · 1997Article
- A new Arabidopsis nucleic-acid-binding protein gene is highly expressed in dividing cells during development.Plant molecular biology · 1997Article
- Splicing of precursors to mRNA in higher plants: mechanism, regulation and sub-nuclear organisation of the spliceosomal machinery.Plant molecular biology · 1996Review
- Splice site prediction in Arabidopsis thaliana pre-mRNA by combining local and global sequence information.Nucleic acids research · 1996Article
- Structure and expression of a plant U1 snRNP 70K gene: alternative splicing of U1 snRNP 70K pre-mRNAs produces two different transcripts.The Plant cell · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three cDNAs encoding RNA-binding proteins were isolated from a tobacco (Nicotiana sylvestris) cDNA library. The predicted proteins (RGP-1) are homologous to each other and consist of a consensus-sequence type RNA-binding domain of 80 amino acids in the N-terminal half and a glycine-rich domain of 61-78 amino acids in the C-terminal half. Nucleic acid-binding assay using the in vitro synthesized RGP-1 protein confirmed that it is an RNA-binding protein. Based on its strong affinity for poly(G) and poly(U), the RGP-1 proteins are suggested to bind specifically to G and/or U rich sequences. All three genes are expressed in leaves, roots, flowers and cultured cells, however, the substantial amount of pre-mRNAs are accumulated especially in roots. Sequence analysis and ribonuclease protection assay indicated that significant amounts of alternatively spliced mRNAs, which are produced by differential selection of 5' splice sites, are also present in various tissues. Tissue-specific alternative splicing was found in two of the three genes. The alternatively spliced mRNAs are also detected in polysomal fractions and are suggested to produce truncated polypeptides. A possible role of this alternative splicing is discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.