Evidence map›Paper›PMID 8370742›Full record

ArticleJournal of clinical microbiology1993

Characterization of an 18-kilodalton Brucella cytoplasmic protein which appears to be a serological marker of active infection of both human and bovine brucellosis.

F A Goldbaum, J Leoni, J C Wallach, C A Fossati

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 93 citations in OpenAlex.

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  18. Brucellosis: an overview.Emerging infectious diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

F A GoldbaumSección Brucelosis, Hospital F. J. Muñíz, Buenos Aires, Argentina.
J Leoni
J C Wallach
C A Fossati
Hospital Muñiz · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some anticytoplasmic protein monoclonal antibodies (MAbs) from mice immunized by infection with Brucella ovis cells have been obtained. One of these MAbs, BI24, was used to purify by immunoaffinity a protein with a pI of 5.6 and a molecular mass of 18 kDa. This protein was present in all of the rough and smooth Brucella species studied, but it could not be detected in Yersinia enterocolitica 09. Three internal peptides of this protein were partially sequenced; no homology with other bacterial proteins was found. The immunogenicity of the 18-kDa protein was studied with both human and bovine sera by a capture enzyme-linked immunosorbent assay system with MAb BI24.

Indexed as

Amino Acid SequenceAnimalsAntibodies, BacterialAntibodies, MonoclonalAntigens, BacterialBacterial ProteinsBrucellaBrucellosisBrucellosis, BovineCattleCytoplasmEnzyme-Linked Immunosorbent AssayHumansImmunoblottingMolecular Sequence DataAntibodies, BacterialAntibodies, MonoclonalAntigens, BacterialBacterial Proteins

Identifiers

PMID8370742
PMCPMC265711
OpenAlexW2112129363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.