ArticleInfection and immunity1993
Association of type II immunoglobulin G-binding protein expression and survival of group A streptococci in human blood.
Article in Infection and immunity, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 37 citations in OpenAlex.
- Effectiveness of antibacterial agents against cell-invading bacteria such as Streptococcus pyogenes and Haemophilus influenzae.BMC microbiology · 2021Article
- Vaccination against rheumatic heart disease: a review of current research strategies and challenges.Current infectious disease reports · 2012Article
- Generation of metabolically diverse strains of Streptococcus pyogenes during survival in stationary phase.Journal of bacteriology · 2009Article
- Intracellular survival of Streptococcus pyogenes in polymorphonuclear cells results in increased bacterial virulence.Infection and immunity · 2003Article
- IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.The EMBO journal · 2002Article
- Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or sequence of the transposon.BMC microbiology · 2001Article
- Inverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection cases.Infection and immunity · 2000Article
- Pathogenesis of group A streptococcal infections.Clinical microbiology reviews · 2000Review
- Absence of SpeB production in virulent large capsular forms of group A streptococcal strain 64.Infection and immunity · 2000Article
- M-like proteins of Streptococcus dysgalactiae.Infection and immunity · 2000Article
- Distinct profiles of immunoglobulin G-binding-protein expression by invasive serotype M1 isolates of Streptococcus pyogenes.Clinical and diagnostic laboratory immunology · 1995Article
- Purification and characterization of a 52-kilodalton immunoglobulin G-binding protein from Streptococcus suis capsular type 2.Journal of bacteriology · 1995Article
- The group A streptococcal virR49 gene controls expression of four structural vir regulon genes.Infection and immunity · 1995Article
- Analysis of genes encoding two unique type IIa immunoglobulin G-binding proteins expressed by a single group A streptococcal isolate.Infection and immunity · 1994Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Expression of immunoglobulin G (IgG)-binding proteins on group A streptococcus strain 64 was monitored on bacteria subjected to sequential passage in human blood. After approximately 10 cycles through human blood, strain 64 demonstrated enhanced levels of IgG-binding protein, including the expression of a type IIa binding molecule with an M(r) of approximately 47,000 present only at very low levels on the parent isolate. Changes in the expression of IgG-binding proteins after passage in human blood were similar to those observed when the same organism was passaged sequentially intraperitoneally in mice. Strain 64, passaged in human blood 23 times, was found to be more virulent than the parent isolate when used to infect mice either intraperitoneally or in a skin air sac. These findings suggest that the expression of IgG-binding proteins may be a common response of group A organisms to pressures exerted by distinct host defense mechanisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.