ArticleMolecular & general genetics : MGG1993
Potentially rapid walking in cellular regulatory networks using the gene-gene interference method in yeast.
Article in Molecular & general genetics : MGG, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 23 citations in OpenAlex.
- A fitness-based interferential genetics approach using hypertoxic/inactive gene alleles as references.Molecular genetics and genomics : MGG · 2009Article
- A potentially general method for the in vivo selection of inhibitory peptides targeted at a specific protein using yeast.Current genetics · 2008Article
- Sir-dependent downregulation of various aging processes.Molecular genetics and genomics : MGG · 2005Article
- Cell wall integrity signaling in Saccharomyces cerevisiae.Microbiology and molecular biology reviews : MMBR · 2005Review
- Suppression of the profilin-deficient phenotype by the RHO2 signaling pathway in Saccharomyces cerevisiae.Genetics · 2000Article
- Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway.Journal of bacteriology · 1999Article
- Detection of antagonistic cellular regulatory functions by the gene-gene interference method in yeast.Current genetics · 1996Article
- DNA insertion system for complex yeast shuttle vectors.Current genetics · 1995Article
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Authors and funding
1 author at 1 institution in 1 country.
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Abstract
The recognition that cellular regulatory circuitry is composed of antagonistic elements has made possible a new approach to the selection of regulatory genes, called the gene-gene interference method. The method was used to identify and isolate genes possibly related in an antagonistic way to protein kinase A. Two such genes were recovered: ART1 encodes a potential regulator of cytokinesis and KAI1 appears to be involved in the Start control. The principles of the gene-gene interference method are discussed, as well as its possible general use for 'walking' within the cellular regulatory networks of eukaryotes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.