ArticleThe Journal of clinical investigation1993
Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model.
Article in The Journal of clinical investigation, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 85 citations in OpenAlex.
- Article
- Review
- Genetic analysis of abdominal fat distribution in SM/J and A/J mice.Journal of lipid research · 2010Article
- SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin.The Journal of biological chemistry · 2004Article
- Haplotype analysis in multiple crosses to identify a QTL gene.Genome research · 2004Article
- A novel mouse Chromosome 2 congenic strain with obesity phenotypes.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2003Article
- Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains.Mammalian genome : official journal of the International Mammalian Genome Society · 2003Article
- Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.The Journal of clinical investigation · 1997Article
- A locus on the X chromosome is linked to body length in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
- Mapping of body weight loci on mouse chromosome X.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Genetic factors in lipoprotein metabolism. Analysis of a genetic cross between inbred mouse strains NZB/BINJ and SM/J using a complete linkage map approach.The Journal of clinical investigation · 1995Article
- Identification of four chromosomal loci determining obesity in a multifactorial mouse model.The Journal of clinical investigation · 1995Article
- Anorexia nervosa viewed as an extreme weight condition: genetic implications.Human genetics · 1995Article
- Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model.The Journal of clinical investigation · 1994Article
- Glycogen synthase: a putative locus for diet-induced hyperglycemia.The Journal of clinical investigation · 1994Article
- Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
We have examined backcross progeny derived from a cross of Mus spretus with C57BL/6J, that range from 1 to 50% carcass lipid (n = 215), and from 22 to 130 mg/dl plasma total cholesterol (n = 238). Statistical analysis revealed that distal mouse chromosome 7 exhibits significant linkage both to plasma total cholesterol (likelihood of the odds [LOD] 5.8) and to carcass lipid (LOD 3.8). A locus on chromosome 6 also shows significant linkage to plasma total cholesterol (LOD 5.6), but no linkage to carcass lipid. Neither chromosomal region contains any previously mapped genes likely to influence lipoprotein metabolism, indicating that novel genetic factors contributing to plasma lipoprotein levels have been identified.
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