ArticleClinical and experimental immunology1993
Elevation of heat shock protein synthesis and hsp gene transcription during monocyte to macrophage differentiation of U937 cells.
Article in Clinical and experimental immunology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 40 citations in OpenAlex.
- Article
- Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis.Pharmaceutical research · 2017Article
- Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis.British journal of pharmacology · 2017Article
- Do not stress, just differentiate: role of stress proteins in hematopoiesis.Cell death & disease · 2015Article
- Dermal exposure to immunostimulants induces changes in activity and proliferation of coelomocytes of Eisenia andrei.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2013Article
- Modulation of heat shock proteins during macrophage differentiation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2012Article
- Heat shock protein 32 in human peripheral blood mononuclear cells: effect of aging and inflammation.Journal of clinical immunology · 2005Article
- Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.British journal of pharmacology · 2004Article
- Expression of heat shock protein 70 (HSP70) at the interface of polymer-implants in vivo.Journal of materials science. Materials in medicine · 2000Article
- Interleukin-10 activates heat-shock protein 90beta gene expression.Immunology · 1999Article
- The nuclear factor interleukin-6 (NF-IL6) and signal transducer and activator of transcription-3 (STAT-3) signalling pathways co-operate to mediate the activation of the hsp90beta gene by interleukin-6 but have opposite effects on its inducibility by heat shock.The Biochemical journal · 1998Article
- Interleukin 6 activates heat-shock protein 90 beta gene expression.The Biochemical journal · 1997Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the phorbol myristate acetate (PMA)-induced differentiation of U937 cells to a macrophage-like phenotype, the levels of the heat shock proteins hsp90, hsp72 and hsp65 increased dramatically to a peak level following 24 h of treatment, and then declined. In contrast, no significant increase was observed in the level of the constitutive hsp73 protein in this process. The observed increases in hsp levels were preceded by an increase in the transcription of each of the genes encoding these hsps, including both of the two genes which encode hsp90. The mechanism of this effect and the possible role of the hsps in the function of differentiated macrophages and in the differentiation process are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.