Evidence map›Paper›PMID 8343110›Full record

ArticleThe Biochemical journal1993

Band 3 HT, a human red-cell variant associated with acanthocytosis and increased anion transport, carries the mutation Pro-868-->Leu in the membrane domain of band 3.

L J Bruce, M M Kay, C Lawrence, M J Tanner

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Article
  3. Mouse models of SLC4-linked disorders of HCOAmerican journal of physiology. Cell physiology · 2018
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. The role of band 3 protein in oxygen delivery by red blood cells.Indian journal of clinical biochemistry : IJCB · 1999
    Article
  9. Article
  10. Article
  11. Article
  12. Differential sensitivity of stilbenedisulfonates in their reaction with band 3 HT (Pro-868-->Leu).Proceedings of the National Academy of Sciences of the United States of America · 1995
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

L J BruceDepartment of Biochemistry, School of Medical Sciences, University of Bristol, U.K.
M M Kay
C Lawrence
M J Tanner
University of Bristol · GB

Funding

MEMBRANE CHANGES IN NEUROLOGIC AND AGING DISEASESR01AG008444 · NIA · UNIVERSITY OF ARIZONA · PI KAY, MARGUERITE M · 1989 to 1994
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CELLULAR &MOLECULAR BIOLOGY OF ALTERED BAND 3R01AG008574 · NIA · UNIVERSITY OF ARIZONA · PI KAY, MARGUERITE M · 1989 to 1991
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NIA NIH HHS AG08444NIA NIH HHS AG08574NIA NIH HHS AG0925
6 · The paper itself

Abstract

1. We have studied band 3 HT, a human red-cell band 3 variant with increased M(r), which is associated with abnormal red-cell shape (acanthocytosis) and increased anion-transport activity. 2. We have shown that the increased M(r) does not result from the presence of the band 3 Memphis mutation, and that the variant band 3 is covalently labelled by 4,4'-di-isothiocyanato-1,2-diphenylethane-2,2'-disulphonic acid (H2DIDS) less readily than normal. 3. cDNA cloning studies show that band 3 HT results from the mutation Pro-868-->Leu, and the possible significance of the mutation in the altered anion-transport activity and cytoskeleton binding properties of band 3 HT is discussed.

Indexed as

Mutation4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAcanthocytesAnion Exchange Protein 1, ErythrocyteAnionsBiological TransportDNAHumansLeucineProline4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAnion Exchange Protein 1, ErythrocyteAnionsDNALeucineProline

Identifiers

PMID8343110
PMCPMC1134360
OpenAlexW2413765059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.