ReviewMicrobiological reviews1993
Roles of calcium ions in hyphal tip growth.
Review in Microbiological reviews, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
53 citing papers in PubMed, 246 citations in OpenAlex.
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- Harnessing Fungi Signaling in Living Composites.Global challenges (Hoboken, NJ) · 2024Article
- Article
- Transcription factors SltA and CrzA reversely regulate calcium homeostasis under calcium-limited conditions.Applied and environmental microbiology · 2023Article
- Hyphopodium-Specific Signaling Is Required for Plant Infection byJournal of fungi (Basel, Switzerland) · 2023Article
- Interaction of calcium responsive proteins and transcriptional factors with the PHO regulon in yeasts and fungi.Frontiers in cell and developmental biology · 2023Review
- Effects and interactions of metal oxides in microparticle-enhanced cultivation of filamentous microorganisms.Engineering in life sciences · 2022Review
- Antifungal Effect of Nanoparticles against COVID-19 Linked Black Fungus: A Perspective on Biomedical Applications.International journal of molecular sciences · 2022Review
- Chitosan-Based Materials: An Overview of Potential Applications in Food Packaging.Foods (Basel, Switzerland) · 2022Review
- Biosolid-Amended Soil Enhances Defense Responses in Tomato Based on Metagenomic Profile and Expression of Pathogenesis-Related Genes.Plants (Basel, Switzerland) · 2021Article
- Assessing the Levisticum officinale Koch. essential oil as a novel preservative for stored chia seeds (Salvia hispanica L.) with emphasis on probable mechanism of action.Environmental science and pollution research international · 2021Article
- Antifungal Effect of Chitosan/Nano-TiOMolecules (Basel, Switzerland) · 2021Article
- Calcium Affects Polyphosphate and Lipid Accumulation in Mucoromycota Fungi.Journal of fungi (Basel, Switzerland) · 2021Article
- Targeting the Active Rhizosphere Microbiome ofFrontiers in microbiology · 2021Article
- Granular Calcite Stimulates Natural Mycorrhization and Growth of White Spruce Seedlings in Peat-Based Substrates in Forest Nursery.Microorganisms · 2020Article
- The Effect of Edible Chitosan Coatings Incorporated withBiomolecules · 2018Article
- Mutual independence of alkaline- and calcium-mediated signalling in Aspergillus fumigatus refutes the existence of a conserved druggable signalling nexus.Molecular microbiology · 2017Article
- Evolutionary dynamics in the fungal polarization network, a mechanistic perspective.Biophysical reviews · 2017Review
- Hyphopodium-Specific VdNoxB/VdPls1-Dependent ROS-Ca2+ Signaling Is Required for Plant Infection by Verticillium dahliae.PLoS pathogens · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A role for Ca2+ in the tip growth process of fungal hyphae and other eukaryotic walled cells has been widely explored, following the earlier indications of their importance by Jaffe, Steer, and their colleagues. Analysis of the literature on fungi, with selected comparison with other tip-growing plant cells, shows that the growth rate and morphology of hyphae are sensitive to factors which influence intracellular Ca2+. These factors include variations in extracellular Ca2+ concentrations, Ca2+ ionophores, inhibitors of Ca2+ transport, and calmodulin- and Ca(2+)-binding dyes and buffers introduced into the cytoplasm. The effects of these agents appear to be mediated by a tip-high gradient of cytoplasmic free Ca2+ which is obligatorily present in all critically examined growing tips. Most recent observations agree that the gradient is very steep, declining rapidly within 10 to 20 microns of the tip. This gradient seems to be generated by the combined effects of an influx of Ca2+, via plasma membrane, possibly stretch-activated, channels localized in the hyphal tip, and subapical expulsion or sequestration of these ions. Expulsion probably involves a plasma membrane Ca(2+)-ATPase, but it is not yet possible to differentiate among mitochondria, endoplasmic reticulum, or vacuoles as the dominant sites of sequestration. It is suggested that regulation of the Ca2+ gradient in turn modulates the properties of the actin-based component of the cytoskeleton, which then controls the extensibility, and, possibly, the synthesis of the hyphal apex. Regulatory feedback mechanisms intrinsic to this model of tip growth regulation are briefly discussed, together with suggestions for future experiments which are crucial to its further elucidation and establishment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.