ArticleThe Journal of cell biology1993
The Golgi stack reassembles during telophase before arrival of proteins transported from the endoplasmic reticulum.
Article in The Journal of cell biology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Multi-step down-regulation of the secretory pathway in mitosis: a fresh perspective on protein trafficking.BioEssays : news and reviews in molecular, cellular and developmental biology · 2013Article
- Sec16A defines the site for vesicle budding from the endoplasmic reticulum on exit from mitosis.Journal of cell science · 2010Article
- Endosomal recycling controls plasma membrane area during mitosis.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Capacity of the Golgi apparatus for cargo transport prior to complete assembly.Molecular biology of the cell · 2006Article
- Mapping the functional domains of the Golgi stacking factor GRASP65.The Journal of biological chemistry · 2005Article
- A direct role for GRASP65 as a mitotically regulated Golgi stacking factor.The EMBO journal · 2003Article
- Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis.Molecular and cellular biology · 2002Article
- Golgi clusters and vesicles mediate mitotic inheritance independently of the endoplasmic reticulum.The Journal of cell biology · 2001Article
- The mitotic phosphorylation cycle of the cis-Golgi matrix protein GM130.The Journal of cell biology · 2000Article
- Role of NAD+ and ADP-ribosylation in the maintenance of the Golgi structure.The Journal of cell biology · 1997Article
- Partitioning of the Golgi apparatus during mitosis in living HeLa cells.The Journal of cell biology · 1997Article
- Reassembly of Golgi stacks from mitotic Golgi fragments in a cell-free system.The Journal of cell biology · 1995Article
- Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cells.The Journal of cell biology · 1994Article
- COP-coated vesicles are involved in the mitotic fragmentation of Golgi stacks in a cell-free system.The Journal of cell biology · 1994Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HeLa cells arrested in prometaphase were pulse-labeled with [35S]methionine and chased in the absence of nocodazole to allow passage through mitosis and into G1. Transport of histocompatibility antigen (HLA) molecules to the medial- and trans-Golgi cisternae was measured by monitoring the resistance to endoglycosidase H and the acquisition of sialic acid residues, respectively. Transport to the plasma membrane was measured using neuraminidase to remove sialic acid residues on surface HLA molecules. The half-time for transport to each of these compartments was about 65-min longer in cells progressing out of mitosis than in G1 cells. This delay was only 5-min longer than the half-time for the fall in histone H1 kinase activity suggesting that inactivation of the mitotic kinase triggers the resumption of protein transport. The half-time for reassembly of the Golgi stack, measured using stereological procedures, was also 65 min, suggesting that both transport and reassembly are triggered at the same time. However, since reassembly was complete within 5 min, whereas HLA took 25 min to reach the medial-cisterna, we can conclude that the Golgi stack has reassembled by the time HLA reaches it.
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