ArticleJournal of clinical pathology1993
Identification of Helicobacter pylori DNA in the mouths and stomachs of patients with gastritis using PCR.
Article in Journal of clinical pathology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it, 228 citations in OpenAlex.
- Periodontal Treatment Is Associated With Improvement in Gastric Helicobacter pylori Eradication: An Updated Meta-analysis of Clinical Trials.International dental journal · 2021Pooled it
- Molecular detection of Helicobacter pylori in saliva of Sri Lankan adults with periodontitis, gastritis or both conditions.BMC oral health · 2026Article
- Article
- Comparative Evaluation of Tongue and Periodontal Pocket Microbiome in Relation toAntibiotics (Basel, Switzerland) · 2025Article
- Evaluating Collection Time of Intragastric Fluid During Endoscopy for Point-of-care Test-based Helicobacter pylori Polymerase Chain Reaction.Internal medicine (Tokyo, Japan) · 2025Article
- Detection ofMicroorganisms · 2022Article
- Lack of Association ofIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- The validity evaluation of different 16srRNA gene primers for helicobacter detection urgently requesting to design new specific primers.Scientific reports · 2022Article
- Periodontal disease and influence of periodontal treatment on disease activity in patients with rheumatoid arthritis and spondyloarthritis.Rheumatology international · 2020Article
- Association between Helicobacter pylori infection and dental pulp reservoirs in Japanese adults.BMC oral health · 2019Article
- Identification ofJournal of pharmacy & bioallied sciences · 2019Article
- Periodontal treatment is more effective in gastric Helicobacter pylori eradication in those patients who maintain good oral hygiene.International dental journal · 2019Article
- Molecular detection ofJournal of dental sciences · 2019Article
- Molecular and clinical analyses of Helicobacter pylori colonization in inflamed dental pulp.BMC oral health · 2018Article
- The use of stool specimens reveals Helicobacter pylori strain diversity in a cohort of adolescents and their family members in a developed country.International journal of medical microbiology : IJMM · 2018Article
- Are the view of Helicobacter pylori colonized in the oral cavity an illusion?Experimental & molecular medicine · 2017Review
- Detection of Helicobacter felis in a cat with gastric disease in laboratory animal facility.Laboratory animal research · 2016Article
- Methods for Detecting the Environmental Coccoid Form of Helicobacter pylori.Frontiers in public health · 2015Review
- Helicobacter pylori identification: a diagnostic/confirmatory method for evaluation.Current microbiology · 2014Article
- Helicobacter pylori and oral pathology: relationship with the gastric infection.World journal of gastroenterology · 2014Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo determine the prevalence of Helicobacter pylori colonisation in the mouths of patients with H pylori gastritis.
methodsA nested polymerase chain reaction test for the 16S ribosomal RNA gene of H pylori was used on saliva, dental plaque, gastric juice and gastric biopsy specimens from patients attending a dyspepsia clinic.
resultsThirteen patients had histologically confirmed Helicobacter associated gastritis. Twelve of these had positive gastric aspirates by PCR. Five had at least one positive oral specimen. Eight patients with normal gastric biopsy specimens had no PCR positive oral specimens or gastric aspirates. All, however, had PCR positive gastric biopsy specimens. In an attempt to determine the origin of these positive results in normal patients, it was shown that biopsy forceps could contaminate specimens with DNA from previous patients.
conclusionThe demonstration of the organism in the mouths of a substantial proportion of dyspeptic patients has major implications for the spread of H pylori and identifies a potential source for reinfection following eradication of the organism from the stomach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.