Evidence map›Paper›PMID 8319976›Full record

ArticleImmunogenetics1993

Genomic structure of the human CD53 gene.

V Korínek, V Horejsí

Abstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

V KorínekInstitute of Molecular Genetics, Academy of Sciences of the Czech Republic, Praha.
V Horejsí
Czech Academy of Sciences · CZCzech Academy of Sciences, Institute of Molecular Genetics · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genomic structure of the gene encoding human pan-leukocyte surface glycoprotein CD53 (a member of the "tetraspan family" of membrane proteins) was determined. The gene consists of eight exons encoding all sequences found in cDNA and is spread over more than 26 kilobases of genomic DNA. The exon-intron organization of the CD53 gene is strikingly similar to the CD63 and TAPA-1 genes, which suggests a close evolutionary relationship between these genes. The 5' end of the gene upstream of the first exon contains at least three close transcription start points (approximately 20 base pairs 5' of the 5' end of the published cDNA). The region upstream of the transcription initiation sites is not G+C rich; it contains potential binding sites for several transcriptional factors but no TATA or CCAAT boxes.

Indexed as

Amino Acid SequenceAntigens, CDAntigens, Differentiation, T-LymphocyteBase SequenceCloning, MolecularHumansMolecular Sequence DataPromoter Regions, GeneticTetraspanin 25Transcription, GeneticAntigens, CDAntigens, Differentiation, T-LymphocyteCD53 protein, humanTetraspanin 25

Identifiers

PMID8319976
OpenAlexW118078240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.