ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1993
The binding and reactions of nucleotides and polynucleotides on iron oxide hydroxide polymorphs.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 67 citations in OpenAlex.
- Unraveling iron oxides as abiotic catalysts of organic phosphorus recycling in soil and sediment matrices.Nature communications · 2024Article
- The Formation of RNA Pre-Polymers in the Presence of Different Prebiotic Mineral Surfaces Studied by Molecular Dynamics Simulations.Life (Basel, Switzerland) · 2022Article
- Stability of DL-Glyceraldehyde under Simulated Hydrothermal Conditions: Synthesis of Sugar-like Compounds in an Iron(III)-Oxide-Hydroxide-Rich Environment under Acidic Conditions.Life (Basel, Switzerland) · 2022Article
- Chance, necessity and the origins of life: a physical sciences perspective.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2017Article
- Hydrothermal Microflow Technology as a Research Tool for Origin-of-Life Studies in Extreme Earth Environments.Life (Basel, Switzerland) · 2017Review
- Adsorption of RNA on mineral surfaces and mineral precipitates.Beilstein journal of organic chemistry · 2017Article
- Interaction of aromatic amines with iron oxides: implications for prebiotic chemistry.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2013Article
- Oligomerization of glycine and alanine catalyzed by iron oxides: implications for prebiotic chemistry.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2012Article
- Links between hydrothermal environments, pyrophosphate, na(+), and early evolution.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2011Article
- Photooxidation of nucleic acids on metal oxides: physico-chemical and astrobiological perspectives.The journal of physical chemistry. C, Nanomaterials and interfaces · 2011Article
- Mineral surfaces, geochemical complexities, and the origins of life.Cold Spring Harbor perspectives in biology · 2010Review
- Nucleic acids bind to nanoparticulate iron (II) monosulphide in aqueous solutions.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2008Article
- Clay catalysis of oligonucleotide formation: kinetics of the reaction of the 5'-phosphorimidazolides of nucleotides with the non-basic heterocycles uracil and hypoxanthine.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1999Article
- Divalent cations modify adsorption of 5'-AMP onto precipitated calcium phosphate: a model for cation modulation of adsorptive processes in primitive aqueous environments.Journal of molecular evolution · 1996Article
- Organic sulfur compounds resulting from the interaction of iron sulfide, hydrogen sulfide and carbon dioxide in an anaerobic aqueous environment.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1996Article
- Catalysis and prebiotic RNA synthesis.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1993Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The iron oxide hydroxide minerals goethite and akaganéite were likely constituents of the sediments present in, for instance, geothermal regions of the primitive earth. They may have adsorbed organics and catalyzed the condensation processes which led to the origins of life. The binding to and reactions of nucleotides and oligonucleotides with these minerals was investigated. The adsorption of adenosine, 5'-AMP, 3'-AMP, 5'-UMP, and 5'-CMP to these minerals was studied. Adenosine did not bind to goethite and akaganéite. The adsorption isotherms for the binding of the nucleotides revealed that they all had close to the same affinity for the mineral. Binding to goethite was about four times stronger than to akaganéite. There was little difference in the adsorption of each nucleotide suggesting the binding was between the negative charge on the phosphate group and the positive charges on the mineral surface. The absence of binding of adenosine is consistent with this explanation. Binding decreases as the pH increases due to the titration of the positive (acidic) centers on the minerals. Two times as many moles of polynucleotides were bound to these minerals as compared to the mononucleotides. Watson-Crick hydrogen bonding of adenosine and 5'-AMP to poly(U) complexes with goethite and akaganéite was observed. There was no interaction of uridine with the poly(U)-goethite complex as expected if Watson-Crick hydrogen bonding is taking place. Neither goethite nor akaganéite catalyzed the oligomerization of the phosphorimidazolide of adenosine (ImpA). The template directed synthesis of oligomers of 5'-GMP on the poly(C) bound to goethite was observed. Higher molecular weight oligomers were observed when the poly(C) was bound to goethite than was found in the absence of the mineral.
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