Trial reportInfection1993
[Complications in pre- versus intraoperative one-time prophylaxis with cefuroxime after biliary surgery].
Trial report in Infection, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The trial was conducted with 66 patients undergoing cholecystectomy. At random, 33 patients received 1.5 g cefuroxime i.v. as a single bolus 20 minutes before surgical incision and 33 patients were injected 20 minutes after incision. The overall incidence of wound infections was 1.51%. In the preoperative group, there was the one wound infection and two patients developed urinary tract infections (incidence of infectious complications 9.1%). In the intraoperative group, one patient developed pneumonia and urinary tract infection and another had urinary tract infection. Wound infections did not occur in this group (incidence of infectious complications 6.1%). Patients with infectious complications had a longer operation time and a longer hospital stay. In conclusion, there was no statistically significant difference in infectious complications when cefuroxime prophylaxis was given preoperatively compared to intraoperative administration.
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