Evidence map›Paper›PMID 8314288›Full record

ReviewInfection1993

[Possibilities for the use of 2nd generation cephalosporins in perioperative antibiotic prophylaxis].

R Engemann

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Infection, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

R EngemannChirurgische Universitätsklinik, Würzburg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perioperative antibiotic prophylaxis has proven to prevent infections in a variety of surgical interventions such as colorectal, biliary and vascular surgery. The antimicrobial spectrum of an antibiotic used for perioperative prophylaxis should include Staphylococcus spp., Streptococcus spp. and Escherichia coli which are among the most frequent pathogens isolated from surgical infections. Second generation cephalosporins provide appropriate activity against these microorganisms. In colorectal surgery, combination with an anti-anaerobic agent is mandatory. During the past few years no major resistance development has been observed against second generation cephalosporins which are used at a dosage of 1.5 to 2 g. A single dose may provide sufficient serum levels for approximately three hours. Prolonged surgical procedures need an additional dose. Single dose prophylaxis with a second generation cephalosporin appears to be an appropriate strategy for infection prevention in surgery with regard to efficiency, safety and costs.

Indexed as

PremedicationBacterial InfectionsBiliary Tract Surgical ProceduresCephalosporinsColonHumansPostoperative ComplicationsRectumStaphylococcal InfectionsSurgical Wound InfectionVascular Surgical ProceduresCephalosporins

Identifiers

PMID8314288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.