ArticleThe EMBO journal1994
Yeast chromosome III: new gene functions.
Article in The EMBO journal, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 108 citations in OpenAlex.
- OrthoRefine: automated enhancement of prior ortholog identification via synteny.BMC bioinformatics · 2024Article
- Quantitative assessment of relationship between sequence similarity and function similarity.BMC genomics · 2007Article
- Bacteriophage T4 genome.Microbiology and molecular biology reviews : MMBR · 2003Review
- Sequence conserved for subcellular localization.Protein science : a publication of the Protein Society · 2002Article
- The past, present and future of genome-wide re-annotation.Genome biology · 2002Review
- Human homolog of the mouse imprinted gene Impact resides at the pericentric region of chromosome 18 within the critical region for bipolar affective disorder.Molecular psychiatry · 2001Article
- Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.Molecular and cellular biology · 2000Article
- High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLalpha.Molecular and cellular biology · 1998Article
- The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family.Nucleic acids research · 1998Article
- Direct interaction between Rsc6 and Rsc8/Swh3,two proteins that are conserved in SWI/SNF-related complexes.Nucleic acids research · 1998Article
- Screening for imprinted genes by allelic message display: identification of a paternally expressed gene impact on mouse chromosome 18.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Extracting protein alignment models from the sequence database.Nucleic acids research · 1997Article
- Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast.Genetics · 1996Article
- Article
- Searching databases of conserved sequence regions by aligning protein multiple-alignments.Nucleic acids research · 1996Article
- Los1p, involved in yeast pre-tRNA splicing, positively regulates members of the SOL gene family.Genetics · 1996Article
- Sequence similarity analysis of Escherichia coli proteins: functional and evolutionary implications.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- New protein functions in yeast chromosome VIII.Protein science : a publication of the Protein Society · 1995Article
- A frameshift error detection algorithm for DNA sequencing projects.Nucleic acids research · 1995Article
- The SEA module: a new extracellular domain associated with O-glycosylation.Protein science : a publication of the Protein Society · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One year after the release of the sequence of yeast chromosome III, we have re-examined its open reading frames (ORFs) by computer methods. More than 61% of the 171 probable gene products have significant sequence similarities in the current databases; as many as 54% have already known functions or are related to functionally characterized proteins, allowing partial prediction of protein function, 11 percentage points more than reported a year ago; 19% are similar to proteins of known three-dimensional structure, allowing model building by homology. The most interesting new identifications include a sugar kinase distantly related to ribokinases, a phosphatidyl serine synthetase, a putative transcription regulator, a flavodoxin-like protein, and a zinc finger protein belonging to a distinct subfamily. Several ORFs have similarities to uncharacterized proteins, resulting in new families in search of a function'. About 54% of ORFs match sequences from other phyla, including numerous fragments in the database of expressed sequence tags (ESTs). Most significant similarities to ESTs are with proteins in conserved families widely represented in the databases. About 30% of ORFs contain one or more predicted transmembrane segments. The increase in the power of functional and structural prediction comes from improvements in sequence analysis and from richer databases and is expected to facilitate substantially the experimental effort in characterizing the function of new gene products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.