Thrombin in inflammation and healing: relevance to rheumatoid arthritis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Activation of the Coagulation Cascade as a Universal Danger Sign.Current issues in molecular biology · 2025
   Review
2. TRPV4 as a therapeutic target for joint diseases.Naunyn-Schmiedeberg's archives of pharmacology · 2015
   Review
3. Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond.Journal of molecular medicine (Berlin, Germany) · 2013
   Review
4. Coagulation and the fibrin network in rheumatic disease: a role beyond haemostasis.Nature reviews. Rheumatology · 2012
   Review
5. Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets.Proceedings of the National Academy of Sciences of the United States of America · 2005
   Article
6. Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis.Arthritis research & therapy · 2005
   Article
7. Amelioration of collagen-induced arthritis by thrombin inhibition.The Journal of clinical investigation · 2001
   Article
8. Effect of thrombin inhibition on synovial inflammation in antigen induced arthritis.Annals of the rheumatic diseases · 2000
   Article
9. Prothrombin deficiency results in embryonic and neonatal lethality in mice.Proceedings of the National Academy of Sciences of the United States of America · 1998
   Article
10. Thrombin receptor expression in rheumatoid and osteoarthritic synovial tissue.Annals of the rheumatic diseases · 1996
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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