Evidence map›Paper›PMID 8302848›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1994

A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family.

M van Zeijl, S V Johann, E Closs, J Cunningham, R Eddy, T B Shows, B O'Hara

Open access · greenAbstract readComparative Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 260 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

M van ZeijlMolecular Biology Research Section, American Cyanamid Company, Pearl River, NY 10965.
S V Johann
E Closs
J Cunningham
R Eddy
T B Shows
B O'Hara
Pearl River Hydraulic Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrovirus infection is initiated by binding of the viral envelope glycoprotein to a cell-surface receptor. The envelope proteins of type C retroviruses of mammals demonstrate similarities in structural organization and protein sequence. These similarities suggest the possibility that retroviruses from different interference groups might use related proteins as receptors, despite the absence of any relationship between retrovirus receptors isolated to date. To investigate this possibility, we have identified a human cDNA clone encoding a protein closely related to the receptor for gibbon ape leukemia virus and have found that it functions as the receptor for the amphotropic group of murine retroviruses. Expression of this protein (GLVR-2) is likely to be a requirement for infection of human cells by amphotropic retroviral vectors for purposes of gene therapy.

Indexed as

Membrane Glycoproteins3T3 CellsAmino Acid SequenceAnimalsCarrier ProteinsCell LineCHO CellsChromosome MappingCloning, MolecularCricetinaeDNA, ComplementaryGene ExpressionGenetic VectorsHumansLeukemia Virus, Gibbon ApeLeukemia Virus, MurineCarrier ProteinsDNA, Complementaryecotropic murine leukemia virus receptorleukemia virus receptor, gibbon apeMembrane GlycoproteinsMembrane ProteinsReceptors, VirusSLC20A2 protein, humanSodium-Phosphate Cotransporter Proteins, Type III

Identifiers

PMID8302848
PMCPMC521475
OpenAlexW2068414038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.