ReviewMicrobiological reviews1993
Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes.
Review in Microbiological reviews, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
147 citing papers in PubMed, 328 citations in OpenAlex.
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- NIa-Pro of sugarcane mosaic virus targets Corn Cysteine Protease 1 (CCP1) to undermine salicylic acid-mediated defense in maize.PLoS pathogens · 2024Article
- Attenuation of Zucchini mosaic virus disease in cucumber plants by mycorrhizal symbiosis.Plant cell reports · 2024Article
- Monkeypox virus: An emerging epidemic.Microbial pathogenesis · 2022Review
- Proteolytic Processing of the Coronavirus Replicase Nonstructural Protein 14 Exonuclease Is Not Required for Virus Replication but Alters RNA Synthesis and Viral Fitness.Journal of virology · 2022Article
- Insertion-and-Deletion Mutations between the Genomes of SARS-CoV, SARS-CoV-2, and Bat Coronavirus RaTG13.Microbiology spectrum · 2022Article
- SARS-CoV-2 3CLpro whole human proteome cleavage prediction and enrichment/depletion analysis.Computational biology and chemistry · 2022Article
- Whole genome characterization of wisteria vein mosaic virus from Iran and its relationship to other members of bean common mosaic virus group.3 Biotech · 2021Article
- AnJournal of biomolecular structure & dynamics · 2021Article
- Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to treat COVID-19.Journal of medical virology · 2021Review
- A survey of jaagsiekte sheep retrovirus (JSRV) infection in sheep in the three northeastern provinces of China.Archives of virology · 2021Article
- Article
- LAMPA, LArge Multidomain Protein Annotator, and its application to RNA virus polyproteins.Bioinformatics (Oxford, England) · 2020Article
- Characterization of a highly divergent Sugarcane mosaic virus from Canna indica L. by deep sequencing.BMC microbiology · 2019Article
- Article
- Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.Virology · 2019Article
- Review
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- Iranian johnsongrass mosaic virus: the complete genome sequence, molecular and biological characterization, and comparison of coat protein gene sequences.Virus genes · 2017Article
87 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Many viruses express their genome, or part of their genome, initially as a polyprotein precursor that undergoes proteolytic processing. Molecular genetic analyses of viral gene expression have revealed that many of these processing events are mediated by virus-encoded proteinases. Biochemical activity studies and structural analyses of these viral enzymes reveal that they have remarkable similarities to cellular proteinases. However, the viral proteinases have evolved unique features that permit them to function in a cellular environment. In this article, the current status of plant and animal virus proteinases is described along with their role in the viral replication cycle. The reactions catalyzed by viral proteinases are not simple enzyme-substrate interactions; rather, the processing steps are highly regulated, are coordinated with other viral processes, and frequently involve the participation of other factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.