Evidence map›Paper›PMID 8300848›Full record

ArticleJournal of muscle research and cell motility1993

Non-homogeneous Ca release in isolated frog skeletal muscle fibres.

M Rozycka, H Gonzalez-Serratos, W Goldman

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of muscle research and cell motility, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M RozyckaDepartment of Biophysics, University of Maryland School of Medicine, Baltimore 21201.
H Gonzalez-Serratos
W Goldman

Funding

E-C COUPLING IN NORMAL AND FATIGUED MUSCLESR01NS017048 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI GONZALEZ-SERRATOS, HUGO LISANDRO · 1985 to 1995
–
NINDS NIH HHS R01-NS17048
6 · The paper itself

Abstract

We have examined the spatial distribution of [Ca2+]i during tetanic stimulation in frog skeletal muscle cells using a fluorescence imaging method. We have found a completely unexpected pattern of Ca release: Ca is released forming gradients composed of spots of very significant and slow fluctuations of calcium release. Our findings could be explained if the calcium release process in skeletal muscle is influenced significantly by [Ca2+]i, such as in cardiac muscle, and suggests that the SR/Ca release control can include the established voltage-dependent plus a cardiac-like process of calcium-induced Ca release and a Ca release inhibition by Ca.

Indexed as

AnimalsCalciumMicroscopy, FluorescenceMusclesRana temporariaSarcoplasmic ReticulumCalcium

Identifiers

PMID8300848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.