ArticleJournal of bacteriology1994
Expression of Caulobacter dnaA as a function of the cell cycle.
Article in Journal of bacteriology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 70 citations in OpenAlex.
- Structures of DnaA domain I reveal a dimer conserved across Actinomycetes.Nucleic acids research · 2026Article
- TheJournal of bacteriology · 2023Article
- ThebioRxiv : the preprint server for biology · 2023Article
- Computational modeling of unphosphorylated CtrA:iScience · 2021Article
- A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability.eLife · 2021Article
- Multilayered control of chromosome replication inBiochemical Society transactions · 2019Review
- Lon recognition of the replication initiator DnaA requires a bipartite degron.Molecular microbiology · 2019Article
- Nutritional Control of DNA Replication Initiation through the Proteolysis and Regulated Translation of DnaA.PLoS genetics · 2015Article
- A stress-induced small RNA modulates alpha-rhizobial cell cycle progression.PLoS genetics · 2015Article
- Identification of essential alphaproteobacterial genes reveals operational variability in conserved developmental and cell cycle systems.Molecular microbiology · 2014Article
- Modularity of the bacterial cell cycle enables independent spatial and temporal control of DNA replication.Current biology : CB · 2011Article
- Regulation of the activity of the dual-function DnaA protein in Caulobacter crescentus.PloS one · 2011Article
- Getting in the loop: regulation of development in Caulobacter crescentus.Microbiology and molecular biology reviews : MMBR · 2010Review
- Feedback control of DnaA-mediated replication initiation by replisome-associated HdaA protein in Caulobacter.Journal of bacteriology · 2009Article
- Temporal controls of the asymmetric cell division cycle in Caulobacter crescentus.PLoS computational biology · 2009Article
- Correct timing of dnaA transcription and initiation of DNA replication requires trans translation.Journal of bacteriology · 2009Article
- Complex regulatory pathways coordinate cell-cycle progression and development in Caulobacter crescentus.Advances in microbial physiology · 2009Review
- A quantitative study of the division cycle of Caulobacter crescentus stalked cells.PLoS computational biology · 2008Article
- A DNA methylation ratchet governs progression through a bacterial cell cycle.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- DnaA couples DNA replication and the expression of two cell cycle master regulators.The EMBO journal · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The initiation of DNA replication is under differential control in Caulobacter crescentus. Following cell division, only the chromosome in the progeny stalked cell is able to initiate DNA replication, while the chromosome in the progeny swarmer cell does not replicate until later in the cell cycle. We have isolated the dnaA gene in order to determine whether this essential and ubiquitous replication initiation protein also contributes to differential replication control in C. crescentus. Analysis of the cloned C. crescentus dnaA gene has shown that the deduced amino acid sequence can encode a 486-amino-acid protein that is 37% identical to the DnaA protein of Escherichia coli. The gene is located 2 kb from the origin of replication. Primer extension analysis revealed a single transcript originating from a sigma 70-type promoter. Immunoprecipitation of a DnaA'-beta-lactamase fusion protein showed that although expression occurs throughout the cell cycle, there is a doubling in the rate of expression just prior to the initiation of replication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.