ArticleJournal of molecular evolution1993
Organization and evolution of an alpha satellite DNA subset shared by human chromosomes 13 and 21.
Article in Journal of molecular evolution, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Article
- Article
- The complete sequence of a human genome.Science (New York, N.Y.) · 2022Article
- Global Repeat Map (GRM): Advantageous Method for Discovery of Largest Higher-Order Repeats (HORs) in Neuroblastoma Breakpoint Family (NBPF) Genes, in Hornerin Exon and in Chromosome 21 Centromere.Progress in molecular and subcellular biology · 2021Article
- Review
- Centromere studies in the era of 'telomere-to-telomere' genomics.Experimental cell research · 2020Review
- Centromere Repeats: Hidden Gems of the Genome.Genes · 2019Review
- Alpha satellite DNA biology: finding function in the recesses of the genome.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2018Review
- Higher-order repeat structure in alpha satellite DNA occurs in New World monkeys and is not confined to hominoids.Scientific reports · 2015Article
- Consensus higher order repeats and frequency of string distributions in human genome.Current genomics · 2007Article
- Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.The Journal of cell biology · 2005Article
- Evidence for a fast, intrachromosomal conversion mechanism from mapping of nucleotide variants within a homogeneous alpha-satellite DNA array.Genome research · 2002Article
- Higher-order organization and compartmentalization of satellite DNA PIM357 in species of the coleopteran genus Pimelia.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2002Article
- The mosaic structure of human pericentromeric DNA: a strategy for characterizing complex regions of the human genome.Genome research · 2000Article
- Interhomologue sequence variation of alpha satellite DNA from human chromosome 17: evidence for concerted evolution along haplotypic lineages.Journal of molecular evolution · 1995Article
- A polymorphic alpha satellite sequence specific for human chromosome 13 detected by oligonucleotide primed in situ labelling (PRINS).Human genetics · 1994Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The structure of the alpha satellite DNA higher-order repeat (HOR) unit from a subset shared by human chromosomes 13 and 21 (D13Z1 and D21Z1) has been examined in detail. By using a panel of hybrids possessing either a chromosome 13 or a chromosome 21, different HOR unit genotypes on chromosomes 13 and 21 have been distinguished. We have also determined the basis for a variant HOR unit structure found on approximately 8% of chromosomes 13 but not at all on chromosomes 21. Genomic restriction maps of the HOR units found on the two chromosome 13 genotypes and on the chromosome 21 genotype are constructed and compared. The nucleotide sequence of a predominant 1.9-kilobasepair HOR unit from the D13Z1/D21Z1 subset has been determined. The DNA sequences of different alpha satellite monomers comprising the HOR are compared, and the data are used to develop a model, based on unequal crossing-over, for the evolution of the current HOR unit found at the centromeres of both these chromosomes.
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