ArticleAntonie van Leeuwenhoek1993
Kinetics of microbial growth with mixtures of carbon sources.
Article in Antonie van Leeuwenhoek, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
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- High throughput parameter estimation and uncertainty analysis applied to the production of mycoprotein from synthetic lignocellulosic hydrolysates.Current research in food science · 2024Article
- Rethinking Aerobic Respiration in the Hyporheic Zone under Variation in Carbon and Nitrogen Stoichiometry.Environmental science & technology · 2023Article
- PFrontiers in bioengineering and biotechnology · 2023Article
- Diversity begets diversity during community assembly until ecological limits impose a diversity ceiling.Molecular ecology · 2021Article
- Enzyme regulation and mutation in a model serial-dilution ecosystem.Physical review. E · 2021Article
- Characterization of volatile fatty-acid utilization in Escherichia coli aiming for robust valorisation of food residues.AMB Express · 2020Article
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- Regulation underlying hierarchical and simultaneous utilization of carbon substrates by flux sensors in Escherichia coli.Nature microbiology · 2020Article
- Galacturonate Metabolism in Anaerobic Chemostat Enrichment Cultures: Combined Fermentation and Acetogenesis by the Dominant sp. nov. "Candidatus Galacturonibacter soehngenii".Applied and environmental microbiology · 2018Article
- Cell-to-cell variation and specialization in sugar metabolism in clonal bacterial populations.PLoS genetics · 2017Article
- Biomethane potential of industrial paper wastes and investigation of the methanogenic communities involved.Biotechnology for biofuels · 2016Article
- Scaling and optimal synergy: Two principles determining microbial growth in complex media.Physical review. E, Statistical, nonlinear, and soft matter physics · 2015Article
- Quantifying the effects of the division of labor in metabolic pathways.Journal of theoretical biology · 2014Article
- A defined, glucose-limited mineral medium for the cultivation of Listeria spp.Applied and environmental microbiology · 2013Article
- Phenomenological model for predicting the catabolic potential of an arbitrary nutrient.PLoS computational biology · 2012Article
- Acetogenesis in the energy-starved deep biosphere - a paradox?Frontiers in microbiology · 2011Article
- Conversion of glycerol to pyruvate by Escherichia coli using acetate- and acetate/glucose-limited fed-batch processes.Journal of industrial microbiology & biotechnology · 2010Article
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3 authors.
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Abstract
Several investigations have shown that during growth in carbon-limited chemostats the simultaneous utilisation of carbon substrates which usually provoke diauxie under batch conditions, i.e., 'mixed substrate growth,' is probably the rule under ecologically relevant growth conditions. In contrast, the models presently available for the description of the kinetics of microbial growth are all based on the use of single substrates. Systematic studies in chemostat culture have shown that steady-state residual concentrations of individual compounds were consistently lower during mixed substrate growth than during growth with the single substrates. This effect is clearly demonstrated for the case of Escherichia coli growing with mixtures of glucose plus galactose. The data presented indicate that the extent of reduction of steady-state residual substrate concentration is dependent on the proportions of the substrates in the mixture, the nature of substrates mixed and the regulation pattern of enzymes involved in their breakdown. If this behaviour can be shown to be typical for growth under environmental conditions, it may provide an explanation why microbes still grow relatively fast at the low substrate concentrations encountered in nature.
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