ArticleImmunogenetics1994
Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region.
Article in Immunogenetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Prognostic and clinicopathological significance of kinesin family member C1 in various cancers: A meta-analysis.Medicine · 2019Pooled it
- IQ Motif Containing GTPase-Activating Protein 3 Is Associated with Cancer Stemness and Survival in Pancreatic Ductal Adenocarcinoma.Pathobiology : journal of immunopathology, molecular and cellular biology · 2024Article
- Kinesin family member C1 accelerates bladder cancer cell proliferation and induces epithelial-mesenchymal transition via Akt/GSK3β signaling.Cancer science · 2019Article
- Molecular carcinogenesis of gastric cancer: Lauren classification, mucin phenotype expression, and cancer stem cells.International journal of clinical oncology · 2019Review
- KIFC1, a novel potential prognostic factor and therapeutic target in hepatocellular carcinoma.International journal of oncology · 2018Article
- Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy.Journal of immunology research · 2018Article
- KIFC1: a promising chemotherapy target for cancer treatment?Oncotarget · 2016Review
- The Msd1-Wdr8-Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies.The Journal of cell biology · 2015Article
- The molecular basis for kinesin functional specificity during mitosis.Cytoskeleton (Hoboken, N.J.) · 2013Review
- Kinesins and cancer.Nature reviews. Cancer · 2012Review
- All kinesin superfamily protein, KIF, genes in mouse and human.Proceedings of the National Academy of Sciences of the United States of America · 2001Review
- Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3.Molecular and cellular biology · 2001Article
- The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindle.The Journal of cell biology · 1999Article
- Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex.Genome research · 1998Article
- XCTK2: a kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts.The Journal of cell biology · 1997Article
- Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.The Journal of cell biology · 1996Article
- Kinesin-related proteins in the mammalian testes: candidate motors for meiosis and morphogenesis.Molecular biology of the cell · 1996Article
- Characterization of a minus end-directed kinesin-like motor protein from cultured mammalian cells.The Journal of cell biology · 1995Article
- Determinants of motor polarity in the kinesin proteins.Biophysical journal · 1995Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We previously reported the presence of a new gene (HSET) with an unknown function, in the centromeric side of the class II gene region of the human major histocompatibility complex (MHC). cDNA clones corresponding to the HSET gene were isolated from a human testis cDNA library. A 2.4 kilobase transcript from the HSET gene was abundantly expressed in testis, B-cell, T-cell, and ovary cell lines but was not detected in lung or stomach. Analysis of the nucleotide sequence of the HSET cDNA clones revealed significant similarity to kinesin-related proteins in yeast, Drosophila, and human. Its predicted amino acid sequence contains a domain with strong sequence similarity to the ATP-binding and motor domains of a plus end-directed microtubule motor protein, kinesin, which might be involved in mitotic chromosome segregation, suggesting that the HSET gene encodes a novel kinesin-related protein.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.