ArticleBiophysical journal1993
A novel method to study the electrodynamic behavior of actin filaments. Evidence for cable-like properties of actin.
Article in Biophysical journal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Measurement and Characterization of the Electrical Properties of Actin Filaments.International journal of molecular sciences · 2024Article
- Article
- Mechanobiology: A landscape for reinterpreting stem cell heterogeneity and regenerative potential in diseased tissues.iScience · 2023Review
- Role of the microtubules in the electrical activity of the primary cilium of renal epithelial cells.Frontiers in molecular biosciences · 2023Article
- CACPPAF, a COMSOL application to characterize polyelectrolyte properties of actin filaments.SoftwareX · 2022Article
- Cytochalasin B Modulates Nanomechanical Patterning and Fate in Human Adipose-Derived Stem Cells.Cells · 2022Article
- Electrical Propagation of Condensed and Diffuse Ions Along Actin Filaments.Journal of computational neuroscience · 2022Article
- Electrical recordings from dendritic spines of adult mouse hippocampus and effect of the actin cytoskeleton.Frontiers in molecular neuroscience · 2022Article
- Bio-Mimicking, Electrical Excitability Phenomena Associated With Synthetic Macromolecular Systems: A Brief Review With Connections to the Cytoskeleton and Membraneless Organelles.Frontiers in molecular neuroscience · 2022Review
- Article
- Electroactive macromolecular motors as model materials of ectotherm muscles.RSC advances · 2021Review
- Java application for cytoskeleton filament characterization (JACFC).Software impacts · 2021Article
- Neuronal Activity in the Sciatic Nerve Is Accompanied by Immediate Cytoskeletal Changes.Frontiers in molecular neuroscience · 2021Article
- Router design for nano-communication using actin quantum cellular automata.IET nanobiotechnology · 2020Article
- Ion-Based Cellular Signal Transmission, Principles of Minimum Information Loss, and Evolution by Natural Selection.International journal of molecular sciences · 2019Article
- Computing on actin bundles network.Scientific reports · 2019Article
- Signal transmission through elements of the cytoskeleton form an optimized information network in eukaryotic cells.Scientific reports · 2019Article
- A multi-scale approach to describe electrical impulses propagating along actin filaments in both intracellular and in vitro conditions.RSC advances · 2018Article
- An Overview of Sub-Cellular Mechanisms Involved in the Action of TTFields.International journal of environmental research and public health · 2016Review
- Long range physical cell-to-cell signalling via mitochondria inside membrane nanotubes: a hypothesis.Theoretical biology & medical modelling · 2016Review
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Actin, one of the most abundant intracellular proteins, forms long linear polyelectrolytic polymers in solution. A novel technique to handle single actin filaments in solution was developed that allows the study of ionic currents elicited along the surface of electrically stimulated actin filaments. Electrical currents were observed about the polymer's surface under both high (100 mM KCl) and low (1 mM KCl) ionic strength conditions. The data are consistent with a dynamic behavior of the counterionic cloud surrounding the actin filaments that support ionic movements along their longitudinal axis upon electrical stimulation. Counterionic waves were highly nonlinear in nature and remained long after the electrical stimulation of the actin filaments ceased. In this report therefore, we demonstrate that actin filaments can function as biological "electrical wires" and can thus be conceptualized as nonlinear inhomogeneous transmission lines. This ability of actin filaments to conduct electrical signals may have important implications in the coupling of intracellular signals.
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Registered trials
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