ArticleProceedings of the National Academy of Sciences of the United States of America1993
Transcriptional regulatory elements downstream of the JunB gene.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- In silico transcriptional regulation and functional analysis of dengue shock syndrome associated SNPs in PLCE1 and MICB genes.Functional & integrative genomics · 2016Article
- Chromatin loop organization of the junb locus in mouse dendritic cells.Nucleic acids research · 2013Article
- Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation.Journal of neuroinflammation · 2012Article
- Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation.Oncogene · 2012Article
- N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem cells from bone marrow.The Journal of biological chemistry · 2011Article
- Degeneration of the mouse retina upon dysregulated activity of serum response factor.Molecular vision · 2011Article
- Constitutive JunB expression, associated with the JAK2 V617F mutation, stimulates proliferation of the erythroid lineage.Leukemia · 2009Article
- Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression.The EMBO journal · 2007Article
- Human T-cell leukemia virus type 1 Tax enhances serum response factor DNA binding and alters site selection.Journal of virology · 2007Article
- Serum response factor binding sites differ in three human cell types.Genome research · 2007Article
- Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependent.BMC molecular biology · 2004Article
- MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts.Molecular and cellular biology · 2002Article
- Platelet-derived growth factor-stimulated expression of the MCP-1 immediate-early gene involves an inhibitory multiprotein complex.Molecular and cellular biology · 1999Article
- Multivalent DNA-binding properties of the HMG-1 proteins.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Expression and activity of serum response factor is required for expression of the muscle-determining factor MyoD in both dividing and differentiating mouse C2C12 myoblasts.Molecular biology of the cell · 1996Article
- Identification of a functional promoter element in the 5'-flanking region of the rat cMG1/TIS11b gene.The Biochemical journal · 1995Article
- A new platelet-derived growth factor-regulated genomic element which binds a serine/threonine phosphoprotein mediates induction of the slow immediate-early gene MCP-1.Molecular and cellular biology · 1995Article
- Ligand-induced desensitization of interleukin 1 receptor-initiated intracellular signaling events in T helper lymphocytes.The Journal of experimental medicine · 1994Article
- BMP enhances transcriptional responses to NGF during PC12 cell differentiation.Neurochemical researchArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
JunB is an immediate early transcription factor that is induced by a variety of extracellular signaling agents, including growth factors, phorbol esters, and agents that elevate cyclic AMP. The mechanism of activation of the gene encoding JunB by these agents is not well understood. By using the JunB gene together with flanking DNA in transfection experiments, we show that a serum response element (SRE) and/or a cAMP response element (CRE) downstream of the gene mediate the response of the gene in mouse NIH 3T3 cells to serum, platelet-derived growth factor, basic fibroblast growth factor, phorbol ester, and forskolin. In addition, a segment of DNA just upstream of the TATA box is required for optimal activation of the gene.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.