ArticleThe EMBO journal1993
Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.
Article in The EMBO journal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 79 citations in OpenAlex.
- RPL6 Interacts with HMGCS1 to Stabilize HIF-1α by Promoting Cholesterol Production in Hepatocellular Carcinoma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
- Dissecting macromolecular recognition sites in ribosome: implication to its self-assembly.RNA biology · 2019Article
- Functional interaction between ribosomal protein L6 and RbgA during ribosome assembly.PLoS genetics · 2014Article
- Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9.Journal of virology · 2013Article
- Viral protein targeting to the cortical endoplasmic reticulum is required for cell-cell spreading in plants.The Journal of cell biology · 2011Article
- A noncognate aminoacyl-tRNA synthetase that may resolve a missing link in protein evolution.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Selecting rRNA binding sites for the ribosomal proteins L4 and L6 from randomly fragmented rRNA: application of a method called SERF.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- From genetic to structural characterization of a new class of RNA-binding domain within the SacY/BglG family of antiterminator proteins.The EMBO journal · 1997Article
- Contact sites of peptide-oligoribonucleotide cross-links identified by a combination of peptide and nucleotide sequencing with MALDI MS.Journal of protein chemistry · 1997Article
- A newly identified Minute locus, M(2)32D, encodes the ribosomal protein L9 in Drosophila melanogaster.Molecular & general genetics : MGG · 1996Article
- Crystal structure of the RNA binding ribosomal protein L1 from Thermus thermophilus.The EMBO journal · 1996Article
- Loop IV of 5S ribosomal RNA has contacts both to domain II and to domain V of the 23S RNA.RNA (New York, N.Y.) · 1996Article
- Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies.The EMBO journal · 1995Article
- X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix.The EMBO journal · 1995Article
- Structures of small subunit ribosomal RNAs in situ from Escherichia coli and Thermomyces lanuginosus.Molecular and cellular biochemistry · 1995Article
- Ribosomal proteins of Thermomyces lanuginosus--characterisation by two-dimensional gel electrophoresis and differential disassembly.Molecular and cellular biochemistry · 1995Article
- Crystal structure of CspA, the major cold shock protein of Escherichia coli.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Stem-loop IV of 5S rRNA lies close to the peptidyltransferase center.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Crystal structure of the ribosomal protein S6 from Thermus thermophilus.The EMBO journal · 1994Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
In all cells, protein synthesis is coordinated by the ribosome, a large ribonucleoprotein particle that is composed of > 50 distinct protein molecules and several large RNA molecules. Here we present the crystal structure of ribosomal protein L6 from the thermophilic bacterium Bacillus stearothermophilus solved at 2.6 A resolution. L6 contains two domains with almost identical folds, implying that it was created by an ancient gene duplication event. The surface of the molecule displays several likely sites of interaction with other components of the ribosome. The RNA binding sites appear to be localized in the C-terminal domain whereas the N-terminal domain contains the potential sites for protein-protein interactions. The domain structure is homologous with several other ribosomal proteins and to a large family of eukaryotic RNA binding proteins.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.