ArticleArchives of virology1993
Determination of human rotavirus VP4 using serotype-specific cDNA probes.
Article in Archives of virology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Rare rotavirus strains in children with severe diarrhea, Malaysia.Emerging infectious diseases · 2011Article
- Rotavirus strains bearing genotype G9 or P[9] recovered from Brazilian children with diarrhea from 1997 to 1999.Journal of clinical microbiology · 2001Article
- VP4 and VP7 genotyping of rotavirus samples recovered from infected children in Ireland over a 3-year period.Journal of clinical microbiology · 1999Article
- Comparison of enzyme immunoassay, PCR, and type-specific cDNA probe techniques for identification of group A rotavirus gene 4 types (P types).Journal of clinical microbiology · 1997Article
- Unusual diversity of human rotavirus G and P genotypes in India.Journal of clinical microbiology · 1996Article
- Survey of equine rotaviruses shows conservation of one P genotype in background of two G genotypes.Archives of virology · 1996Article
- Prevalence of G and P serotypes among equine rotaviruses in the faeces of diarrhoeic foals.Archives of virology · 1996Article
- Heterogeneity of VP4 neutralization epitopes among serotype P1A human rotavirus strains.Clinical and diagnostic laboratory immunology · 1995Article
- Characterization of rotavirus strains from newborns in New Delhi, India.Journal of clinical microbiology · 1994Article
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Authors and funding
3 authors.
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Abstract
The VP4 genetic groups of 151 field strains of human rotaviruses obtained from infants and young children with diarrhea from four locations in Malaysia were analyzed. The strains were adapted to growth in tissue culture and studied further by molecular hybridization of northern blotted RNA to PCR-generated cDNA probes representing amino acids 84-180 of the KU strain VP4, 83-181 of the DS-1 strain VP4, and 83-180 of either the 1076 or K8 strain VP4, representing VP4 genetic groups 1-4 (P1A, P1B, P2, and P3), respectively. The majority (79% of the field strains hybridized with the KU VP4 genetic group 1 probe and were associated with G1, G3, G4, untypable, or mixed G serotypes. VP4 genetic group 1 (P1A) strains were the most common in all locations in Malaysia between 1978-1988. Three strains which exhibited G3 and subgroup I specificity hybridized with the K8 VP4 genetic group 4 probe. These three VP4 genetic group 4 (P3) strains were detected in two different years and locations, extending the initial detection of this VP4 genetic group (the K8 strain) in Japan to a larger geographical area of Asia.
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