ArticleJournal of virology1994
Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis.
Article in Journal of virology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 104 citations in OpenAlex.
- Patch type nucleotide sequence identities between genomes from many different species facilitate illegitimate recombination.Scientific reports · 2026Article
- Virus Infection and mRNA Nuclear Export.International journal of molecular sciences · 2023Review
- Strength in Diversity: Nuclear Export of Viral RNAs.Viruses · 2020Review
- Competitive Inhibition of Lysine Acetyltransferase 2B by a Small Motif of the Adenoviral Oncoprotein E1A.The Journal of biological chemistry · 2016Article
- Computational analysis of human adenovirus serotype 18.Virology · 2010Article
- The revolution in viral genomics as exemplified by the bioinformatic analysis of human adenoviruses.Viruses · 2010Article
- Unique sequence features of the Human adenovirus 31 complete genomic sequence are conserved in clinical isolates.BMC genomics · 2009Article
- Occurrence of human adenoviruses at two recreational beaches of the great lakes.Applied and environmental microbiology · 2007Article
- Epigenetic status of an adenovirus type 12 transgenome upon long-term cultivation in hamster cells.Journal of virology · 2007Article
- Characterizations of adenovirus type 41 isolates from children with acute gastroenteritis in Japan, Vietnam, and Korea.Journal of clinical microbiology · 2004Article
- Human adenovirus type 35: nucleotide sequence and vector development.Gene therapy · 2003Article
- Rapid typing of human adenoviruses by a general PCR combined with restriction endonuclease analysis.Journal of clinical microbiology · 2001Article
- Species-specific identification of human adenoviruses by a multiplex PCR assay.Journal of clinical microbiology · 2000Article
- PCR and restriction endonuclease analysis for rapid identification of human adenovirus subgenera.Journal of clinical microbiology · 2000Article
- Review
- Role of alpha(v) integrins in adenovirus cell entry and gene delivery.Microbiology and molecular biology reviews : MMBR · 1999Review
- Mechanisms of T-cell activation by human T-cell lymphotropic virus type I.Microbiology and molecular biology reviews : MMBR · 1999Review
- The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F.Journal of virology · 1998Article
- Nucleotide sequence, genome organization, and transcription map of bovine adenovirus type 3.Journal of virology · 1998Article
- Characterization of bovine adenovirus type 3 early region 2B.Virus genes · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A fresh inoculum of human adenovirus type 12 (Ad12) was obtained from the American Type Culture Collection and passaged once on human embryonic kidney cells, and Ad12 DNA was prepared from the first-passage yield to avoid higher passages which might have generated host-virus DNA recombinants. The 18 PstI fragments of Ad12 DNA were cloned into the pBluescript KS vector, and the entire nucleotide sequence of both strands from all 18 fragments was determined by using successive oligodeoxyribonucleotide primers. Ad12 DNA extends over 34,125 nucleotide pairs, and its molecular weight is calculated to be about 22 x 10(6). The nucleotide sequence of Ad12 DNA was subjected to computer analyses that determined possible open reading of frames on the two strands, the leader sequences, the position of the virus-associated RNA coding region, possible TATA, and polyadenylation signals. The distribution of the Ad12 open reading frames was similar to that in the previously sequenced Ad2 DNA, but there were also distinct differences. Ad12 DNA has an inverted terminal redundancy of 161 nucleotides, compared with 102 nucleotides in Ad2 DNA. There were stretches of sequence identity between Ad2 and Ad12 DNAs at both termini; the overall sequence similarity between the two viral genomes ranged between 59% (polypeptide IX) and 77% (in the E2 region), with high homology also in the sequences for the adenovirus DNA polymerase.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.