ArticleThe Journal of cell biology1993
Targeting and mistargeting of plasma membrane adaptors in vitro.
Article in The Journal of cell biology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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Who cites it
39 citing papers in PubMed.
- The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein GScientific reports · 2017Article
- MEX3C interacts with adaptor-related protein complex 2 and involves in miR-451a exosomal sorting.PloS one · 2017Article
- Article
- Supported native plasma membranes as platforms for the reconstitution and visualization of endocytic membrane budding.Methods in cell biology · 2012Article
- Clathrin-mediated entry and cellular localization of chlorotoxin in human glioma.Cancer cell international · 2011Article
- The role of cargo proteins in GGA recruitment.Traffic (Copenhagen, Denmark) · 2007Article
- Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins.Molecular biology of the cell · 2005Article
- The aftiphilin/p200/gamma-synergin complex.Molecular biology of the cell · 2005Article
- Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins.The Journal of cell biology · 2004Article
- EpsinR: an ENTH domain-containing protein that interacts with AP-1.Molecular biology of the cell · 2003Article
- CASP, the alternatively spliced product of the gene encoding the CCAAT-displacement protein transcription factor, is a Golgi membrane protein related to giantin.Molecular biology of the cell · 2002Article
- GGAs: roles of the different domains and comparison with AP-1 and clathrin.Molecular biology of the cell · 2001Article
- The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- The many ways to cross the plasma membrane.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome.The Journal of cell biology · 2000Article
- Characterization of a fourth adaptor-related protein complex.Molecular biology of the cell · 1999Article
- ADP-ribosylation factor 1 dependent clathrin-coat assembly on synthetic liposomes.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Article
- The molecular characterization of transport vesicles.Plant molecular biology · 1998Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Targeting and recruitment of the plasma membrane (PM) clathrin-coated vesicle adaptor complexes has been studied using an in vitro system based on permeabilized acceptor cells and donor cytosol. Through the use of species- and/or tissue-specific antibodies, only newly recruited exogenous PM adaptors are visualized. Targeting of PM adaptors can be switched from the plasma membrane to a perinuclear compartment by GTP gamma S or excess calcium. Prior treatment with brefeldin A prevents GTP gamma S-induced mistargeting. Double-labeling immunofluorescence and immunogold EM indicate that the perinuclear PM adaptor binding compartment is late endosomal. We propose that receptors for PM adaptors cycle between the plasma membrane and an endosomal storage compartment. Normally the receptors would be switched on only at the plasma membrane, but both GTP gamma S and calcium are capable of reversing this switch. Intracellular sequestration of PM adaptor receptors may provide the cell with a mechanism for up-regulating endocytosis following a burst of exocytosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.