ArticleBiophysical journal1993
Crowding-induced organization of cytoskeletal elements: I. Spontaneous demixing of cytosolic proteins and model filaments to form filament bundles.
Article in Biophysical journal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 47 citations in OpenAlex.
- Macromolecular Crowding and DNA: Bridging the Gap between In Vitro and In Vivo.International journal of molecular sciences · 2023Review
- Large and stable: actin aster networks formedFrontiers in chemistry · 2022Article
- Macromolecular crowding amplifies adipogenesis of human bone marrow-derived mesenchymal stem cells by enhancing the pro-adipogenic microenvironment.Tissue engineering. Part A · 2014Article
- Molecular crowding of collagen: a pathway to produce highly-organized collagenous structures.Biomaterials · 2012Article
- Macromolecular crowding directs extracellular matrix organization and mesenchymal stem cell behavior.PloS one · 2012Article
- Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin.The EMBO journal · 2009Article
- Microtubule bundling and nested buckling drive stripe formation in polymerizing tubulin solutions.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Micro- and macrorheological properties of actin networks effectively cross-linked by depletion forces.Biophysical journal · 2006Article
- Cell-volume-dependent vascular smooth muscle contraction: role of Na+, K+, 2Cl- cotransport, intracellular Cl- and L-type Ca2+ channels.Pflugers Archiv : European journal of physiology · 2004Article
- Heterogeneous nucleation and crowding in sickle hemoglobin: an analytic approach.Biophysical journal · 2002Article
- Flexible polymer-induced condensation and bundle formation of DNA and F-actin filaments.Biophysical journal · 2001Article
- Regulated phase transitions of bacterial chromatin: a non-enzymatic pathway for generic DNA protection.The EMBO journal · 2001Article
- Dynamics of the mitochondrial reticulum in live cells using Fourier imaging correlation spectroscopy and digital video microscopy.Biophysical journal · 2000Article
- Nonideality and the nucleation of sickle hemoglobin.Biophysical journal · 2000Article
- Tracer diffusion through F-actin: effect of filament length and cross-linking.Biophysical journal · 1996Article
- The bundling of actin with polyethylene glycol 8000 in the presence and absence of gelsolin.Biophysical journal · 1996Article
- Crowding-induced organization of cytoskeletal elements: II. Dissolution of spontaneously formed filament bundles by capping proteins.The Journal of cell biology · 1994Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The theory for the effects of crowding on the behavior of reversibly self-assembling solutes is extended to mixtures containing nonassembling solutes. The theory predicts that excluded volume will cause dramatic demixing into domains of long, tightly packed, highly aligned fibers coexisting with an isotropic solution of unaggregated species. It suggests that the bundling of fibers in cells is entropically driven and that accessory binding proteins in the cytoplasm serve to modulate the process rather than create it.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.