ArticleNucleic acids research1993
A pre-export U1 snRNP in Xenopus laevis oocyte nuclei.
Article in Nucleic acids research, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands.Nucleic acids research · 2021Article
- The Herpesvirus saimiri small nuclear RNAs recruit AU-rich element-binding proteins but do not alter host AU-rich element-containing mRNA levels in virally transformed T cells.Molecular and cellular biology · 2004Article
- RNA-mediated interaction of Cajal bodies and U2 snRNA genes.The Journal of cell biology · 2001Article
- Transport of macromolecules between the nucleus and the cytoplasm.RNA (New York, N.Y.) · 1998Review
- AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation.Genes & development · 1997Article
- The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways.The Journal of cell biology · 1997Article
- A common maturation pathway for small nucleolar RNAs.The EMBO journal · 1995Article
- NMR studies of U1 snRNA recognition by the N-terminal RNP domain of the human U1A protein.The EMBO journal · 1994Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We demonstrate that precursors of U1 snRNA are associated with nuclear proteins prior to export to the cytoplasm. The approximately 15S complexes containing pre-U1 RNA, which we call pre-export U1 snRNPs, were identified in extracts of Xenopus laevis oocyte nuclei that were synthesizing U1 RNAs from injected U1 genes. The U1 snRNP-specific A protein was associated with nuclear pre-U1 RNA since both this protein and the RNA were co-precipitated by antibodies directed against either the m7G-cap of the precursor RNA or the U1-A protein. The interaction of the U1-A protein with pre-U1 RNA required sequences in the loop II region although this region of U1 RNA was not necessary for the association of U1 A protein with mature U1 snRNPs. The U1 A protein helps protect pre-U1 RNA against degradation in the nucleus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.