ArticleJournal of bacteriology1993
The Vibrio fischeri luminescence gene activator LuxR is a membrane-associated protein.
Article in Journal of bacteriology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 48 citations in OpenAlex.
- Core elements play distinct roles in promoter birth and transcriptional regulation.Nature communications · 2026Article
- Quorum sensing intervened bacterial signaling: Pursuit of its cognizance and repression.Journal, genetic engineering & biotechnology · 2018Review
- Single-molecule tracking in live Vibrio cholerae reveals that ToxR recruits the membrane-bound virulence regulator TcpP to the toxT promoter.Molecular microbiology · 2015Article
- Imaging live cells at the nanometer-scale with single-molecule microscopy: obstacles and achievements in experiment optimization for microbiology.Molecules (Basel, Switzerland) · 2014Review
- Characterization of a Vibrio fischeri aminopeptidase and evidence for its influence on an early stage of squid colonization.Journal of bacteriology · 2012Article
- Analysis of LuxR regulon gene expression during quorum sensing in Vibrio fischeri.Journal of bacteriology · 2007Article
- Phenazines and their role in biocontrol by Pseudomonas bacteria.The New phytologist · 2003Review
- LasR, a transcriptional activator of Pseudomonas aeruginosa virulence genes, functions as a multimer.Journal of bacteriology · 2002Article
- Mob psychology.Journal of bacteriology · 2002Review
- A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Quorum-sensing signal binding results in dimerization of TraR and its release from membranes into the cytoplasm.The EMBO journal · 2000Article
- Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals.Journal of bacteriology · 1999Article
- Synergistic binding of the Vibrio fischeri LuxR transcriptional activator domain and RNA polymerase to the lux promoter region.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Characterization of aarA, a pleiotrophic negative regulator of the 2'-N-acetyltransferase in Providencia stuartii.Journal of bacteriology · 1994Article
- Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators.Journal of bacteriology · 1994Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Vibrio fischeri luminescence (lux) genes are activated at sufficiently high culture densities by the transcriptional activator LuxR in combination with a diffusible signal compound termed autoinducer. We have used antibodies directed against LuxR in immunoprecipitation experiments to study the subcellular location of this transcription factor. The LuxR polypeptide was detected in membranes and not in the soluble pool of cytoplasmic proteins from V. fischeri. LuxR was not released from the membranes by 0.6 M KCl or by the nonionic detergents Nonidet P-40, N-octyl-beta-D-glucopyranoside, and Triton X-100. LuxR and a number of other V. fischeri proteins were released from the membranes by EDTA. The autoinducer had no detectable influence on the subcellular location of LuxR. In spheroplasts, neither the abundance nor the molecular mass of the LuxR antigen was influenced by treatment with proteinase K. Together with other information, these results indicate that LuxR is an amphipathic protein that is associated with the cytoplasmic membrane of V. fischeri.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.