ArticleBritish journal of industrial medicine1993
Mortality from lung cancer in Ontario uranium miners.
Article in British journal of industrial medicine, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 66 citations in OpenAlex.
- Characterizing occupational radon exposure greater than 100 Bq/mScientific reports · 2022Article
- Mining is bad for health: a voyage of discovery.Environmental geochemistry and health · 2020Article
- Histopathologic Analysis of Lung Cancer Incidence Associated with Radon Exposure among Ontario Uranium Miners.International journal of environmental research and public health · 2018Article
- Radon exposure and lung cancer: risk in nonsmokers among cohort studies.Annals of occupational and environmental medicine · 2016Review
- Occupational radon exposure and lung cancer mortality: estimating intervention effects using the parametric g-formula.Epidemiology (Cambridge, Mass.) · 2014Article
- Biogeochemical behaviour and bioremediation of uranium in waters of abandoned mines.Environmental science and pollution research international · 2013Review
- Exposure assessment for a cohort of workers at a former uranium processing facility.Journal of exposure science & environmental epidemiology · 2012Article
- Lung cancer in a U.S. population with low to moderate arsenic exposure.Environmental health perspectives · 2009Article
- Arsenite alters global histone H3 methylation.Carcinogenesis · 2008Article
- Cancer risk around the nuclear power plants of Trillo and Zorita (Spain).Occupational and environmental medicine · 2003Article
- Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Clinical measures, smoking, radon exposure, and risk of lung cancer in uranium miners.Occupational and environmental medicine · 1996Article
- Review
- Ionizing radiation: future etiologic research and preventive strategies.Environmental health perspectives · 1995Article
- Does occupational exposure to dust prevent colorectal cancer?Occupational and environmental medicine · 1995Article
- Radiographic abnormalities and the risk of lung cancer among workers exposed to silica dust in Ontario.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 1995Article
- Neoplastic transformation of human small airway epithelial cells induced by arsenic.Molecular medicine (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mortality from lung cancer was greater in Ontario uranium miners than in the general male population of Ontario (observed = 152, expected = 67.6, standardised mortality ratio 225, 95% confidence interval 191-264). Part of the excess of lung cancer may be because the proportion of men who are smokers or have smoked is greater in uranium miners than in Ontario men. Smoking does not explain the whole excess. Mortality from lung cancer in Ontario uranium miners is clearly related to exposure to short lived radon progeny. The excess relative risk of lung cancer from the same degree of exposure to short lived radon progeny is greatest five to 14 years after exposure and less subsequently. It is greater in men under the age of 55 years and less in older men. Part of the excess of lung cancer mortality in Ontario uranium miners is probably also due to exposure to arsenic that occurred earlier in gold mines. In Ontario uranium miners, the lung cancer mortality from exposure to arsenic increases as the intensity of exposure to short lived radon progeny increases. This finding is consistent with the hypothesis that the risk of lung cancer from exposure to arsenic is enhanced by exposure to other carcinogens. In Ontario uranium miners, the proportion of lung cancers that are small cell carcinomas is greater than in the general population. The proportion of small cell carcinomas is especially great five to 14 years after exposure to short lived radon progeny and in men who die from lung cancer at younger ages.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.