ArticleThe Biochemical journal1993
Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null polymorphisms at the glutathione S-transferase, GSTM1 locus.
Article in The Biochemical journal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- The associations between two vital GSTs genetic polymorphisms and lung cancer risk in the Chinese population: evidence from 71 studies.PloS one · 2014Pooled it
- Influence of genetic polymorphisms in glutathione-S-transferases gene in response to imatinib among Brazilian patients with chronic myeloid leukemia.Molecular biology reports · 2021Article
- Peripheral blood mononuclear cell traffic plays a crucial role in mother-to-infant transmission of hepatitis B virus.International journal of biological sciences · 2015Article
- Polymorphisms of NRF2 and NRF2 target genes in urinary bladder cancer patients.Journal of cancer research and clinical oncology · 2014Article
- Risk association of meningiomas with MTHFR C677T and GSTs polymorphisms: a meta-analysis.International journal of clinical and experimental medicine · 2014Article
- Estrogen-related genes and their contribution to racial differences in breast cancer risk.Cancer causes & control : CCC · 2012Article
- Frequencies of glutathione s-transferase (GSTM1, GSTM3 AND GSTT1) polymorphisms in a Malaysian population.Archives of medical science : AMS · 2011Article
- Superoxide dismutase, catalase, glutathione peroxidase and gluthatione S-transferases M1 and T1 gene polymorphisms in three Brazilian population groups.Genetics and molecular biology · 2011Article
- Polymorphisms in genes related to activation or detoxification of carcinogens might interact with smoking to increase renal cancer risk: results from The Netherlands Cohort Study on diet and cancer.World journal of urology · 2008Article
- Antioxidant defense markers modulated by glutathione S-transferase genetic polymorphism: results of lung cancer case-control study.Genes & nutrition · 2007Article
- Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk.British journal of cancer · 2003Article
- Allelotype influence at glutathione S-transferase M1 locus on breast cancer susceptibility.British journal of cancer · 1999Article
- Susceptibility to multiple cutaneous basal cell carcinomas: significant interactions between glutathione S-transferase GSTM1 genotypes, skin type and male gender.British journal of cancer · 1996Article
- gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?The American journal of pathology · 1995Review
- Progression of cervical intraepithelial neoplasia to cervical cancer: interactions of cytochrome P450 CYP2D6 EM and glutathione s-transferase GSTM1 null genotypes and cigarette smoking.British journal of cancer · 1994Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe the identification of the GSTM1 null, GSTM1 A, GSTM1 B and GSTM1 A,B polymorphisms at the glutathione S-transferase GSTM1 locus using a single-step PCR method. Target DNA was amplified using primers to intron 6 and exon 7 with site-directed mutagenesis being used to introduce a restriction site in DNA amplified from GSTM1 *A, thereby allowing differentiation of this allele and GSTM1 *B. The accuracy of this approach in identifying the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null polymorphisms was confirmed by comparison with, firstly, an established PCR method that distinguishes GSTM1 *0 homozygotes from individuals with the other GSTM1 genotypes and, secondly, GSTM1 phenotypes determined using chromatofocusing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.